AC 187 Datasheet DC Chemicals

Description	AC 187 is an orally active, potent amylin receptor antagonist (IC50= 0.48 nM) that displays 38-fold and 400-fold selectivity over calcitonin and CGRP receptors respectively. AC 187 blocks amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. AC 187 increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels and increases food intake in vivo.
Cat.No	DC41826
Name	AC 187

Chemical Properties

CAS	151804-77-2
Formula	C127H205N37O40
MW	2890.25
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

References

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