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AC 187

  Cat. No.:  DC41826  
Chemical Structure
151804-77-2
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More than 5000 active chemicals with high quality for research!
Field of application
AC 187 is an orally active, potent amylin receptor antagonist (IC50= 0.48 nM) that displays 38-fold and 400-fold selectivity over calcitonin and CGRP receptors respectively. AC 187 blocks amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. AC 187 increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels and increases food intake in vivo.
Chemicals PropertiesBiological activity Related products COA MSDS Datasheet
Cas No.: 151804-77-2
Chemical Name: AC 187
Synonyms: Ac-VLGKLSQELHKLQTYPRTNTGSNTY-NH2
Formula: C127H205N37O40
M.Wt: 2890.25
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
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