BMS-195614 Datasheet DC Chemicals
Description BMS-195614 is a potent, orally bioavailable RARα antagonist (Ki = 2.5 nM) that modulates multiple signaling pathways. It upregulates Bcl2 expression while suppressing NF-κB, AP-1, and PPAR transactivation. Additionally, it reduces IL-6 and VEGF production, mitigates phototoxic damage from blue light, and exhibits anti-migratory, anti-inflammatory, and anti-angiogenic properties.
Cat.No DC43336
Name BMS-195614

Chemical Properties

CAS 182135-66-6
Formula C29H24N2O3
MW 448.512467384338
Storage 0°C (short term), -20°C (long term), desiccated

References

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