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BMS-195614

  Cat. No.:  DC43336   Featured
Chemical Structure
182135-66-6
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More than 5000 active chemicals with high quality for research!
Field of application
BMS-195614 is a potent, orally bioavailable RARα antagonist (Ki = 2.5 nM) that modulates multiple signaling pathways. It upregulates Bcl2 expression while suppressing NF-κB, AP-1, and PPAR transactivation. Additionally, it reduces IL-6 and VEGF production, mitigates phototoxic damage from blue light, and exhibits anti-migratory, anti-inflammatory, and anti-angiogenic properties.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 182135-66-6
Chemical Name: Bms 195614/bms 614
Synonyms: Bms 195614/bms 614;4-[5,6-Dihydro-5,5-dimethyl-8-(quinolin-3-yl)naphthalen-2-carboxamido] benzoic acid; 4-[[[5,6-Dhydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]-benzoic acid;BMS 614;BMS-195614;BMS-614;BMS195614;BMS614
SMILES: CC1(C)CC=C(C2=CN=C3C=CC=CC3=C2)C4=C1C=CC(=C4)C(=O)NC5=CC=C(C=C5)C(=O)O
Formula: C29H24N2O3
M.Wt: 448.512467384338
Purity: >98%
Sotrage: 0°C (short term), -20°C (long term), desiccated
MSDS
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MSDS_26958_DC43336_253310-42-8
COA
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