HQ005 Datasheet DC Chemicals

Description	HQ005 is a highly efficient molecular glue degrader that induces the selective degradation of Cyclin K (CCNK) with exceptional potency (DC50 = 41 nM). By facilitating novel protein-protein interactions between CCNK and the ubiquitin-proteasome system, HQ005 promotes targeted ubiquitination and proteasomal clearance of CCNK, offering a precise pharmacological tool for modulating CDK12/13-dependent transcription and DNA damage response pathways.
Cat.No	DC72726
Name	HQ005

Chemical Properties

CAS	2750644-31-4
Formula	C15H15N5O2S2
MW	361.44
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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