Home > Antibody Drug Conjugates > ADC Cytotoxin
Cat. No. Product name CAS No.
DC8540 DM-1(Mertansine)

A cytotoxic agent used in antibody-drug conjugates

139504-50-0
DC11600 D211

A novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs).

1971075-99-6
DC8802 Maytansinol(Ansamitocin P-0)

Ansamitocin P-0

57103-68-1
DC8241 Ansamitocin P-3

Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29.

66547-09-9
DC11275 Calicheamicin

Calicheamicin is a potent DNA-damaging cytotoxic agent.

108212-75-5
DC9331 Daun02

Daun02 is a daunorubicin b-galactoside prodrug for use in conjunction.

290304-24-4
DC7069 Daunorubicin HCL

Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.

23541-50-6
DC7648 PNU159682

PNU-159682 is a major bioactive metabolite of Nemorubicin in human liver microsomes; > 3,000-fold cytotoxic than its parent compound(MMDX and doxorubicin).

202350-68-3
DC11012 SG3199

SG3199 is a PBD dimer warhead component of antibody-drug conjugate (ADC) payload tesirine, demonstrates potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines with mean GI50 of 151.5 pM.

1595275-71-0
DC11601 SGD-1882

SGD-1882 (PBD dimer, Pyrrolobenzodiazepine dimer) is a novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs)..

1222490-34-7
DC7021 Monomethyl auristatin E (vedotin)

Monomethyl auristatin E (MMAE; Vedotin) is a hot topic in Antibody-drug conjugates (ADCs) studies. It is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin.

474645-27-7
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