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Cat. No. Product name CAS No.
DC11823 BMS-929075

A highly potent, selective, orally bioavailable HCV NS5B polymerase inhibitor with IC50 of 9, 4, and 18 nM for GT1a, GT1b, and GT1b-C316N mutant in HCV replicon assay, respectively.

1217338-97-0
DC11825 MK-8876

A novel, broadly acting non-nucleoside inhibitor of HCV NS5B polymerase with IC50 of 3 nM and 2 nM for GT1b and GT2a, respectively.

1426960-33-9
DC11731 Ruzasvir

A potent, pan-genotype HCV NS5A inhibitor with replicon EC90 of 0.003, 0.016, 0.067, 0.036, 0.007, and 0.007 nM for GT1a, GT1a L31V, GT1a Y93H, GT2b, GT3a, and Gt4a, respectively..

1613081-64-3
DC7541 Balapiravir

Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479).

690270-29-2
DC5077 Boceprevir(EBP 520; SCH 503034 ) Featured

Boceprevir(EBP 520; SCH 503034 ) is useful for Anti HCV.

394730-60-0
DC11081 Coblopasvir

Coblopasvir (KW136, KW-136) is a novel HCV NS5A inhibitor under development for treatment of HCV infection..

1312608-46-0
DC11214 Cyclophilin inhibitor C31

Cyclophilin inhibitor C31 (SMCypI C31) is a small-molecule cyclophilin (CypA) inhibitor (SMCypI) with PPIase inhibition IC50 of 0.1 uM, displays anti-HCV activity (HCV Gt1b replicon EC50=0.4 uM) and disrupts the CypA-NS5A interaction.

DC7394 Daclatasvir dihydrochloride (BMS-790052) Featured

Daclatasvir (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture.

1009119-65-6
DC8238 Danoprevir (RG7227) Featured

Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A.

850876-88-9
DC10818 ABT-493(Glecaprevir) Featured

Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM.

1365970-03-1
DC11494 INX-08189

INX-08189 is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay.

1234490-83-5
DC8178 Beclabuvir(BMS-791325)

non-nucleoside inhibitor of the NS5B

958002-33-0
DC8183 Paritaprevir(Veruprevir ABT-450) Featured

NS3/4A protease inhibitor

1216941-48-8
DC10728 Pibrentasvir(ABT-530) Featured

Pibrentasvir is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6.

1353900-92-1
DC4121 PSI6130 Featured

PSI-6130(R 1656) is a Hepatitis C Virus Nucleoside Inhibitor. PSI-6130(R 1656) is useful for Antiviral agents.

817204-33-4
DC9462 R-7128

R-7128(Mericitabine) is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, with activity across all HCV genotypes.

940908-79-2
DC8190 Ravidasvir hydrochloride (PPI-668) Featured

Ravidasvir(PPI-668) is a NS5A Inhibitor.

1303533-81-4
DC8612 Simeprevir(TMC-435)

Simeprevir (TMC 435350) is a potent inhibitor of HCV NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM).

923604-59-5
DC9463 Tegobuvir (GS-9190; GS 333126) Featured

Tegobuvir (GS-9190; GS 333126) is a non-nucleoside nonstructural protein (NS)5B polymerase inhibitor.

1000787-75-6
DC1008 Telaprevir (VX-950) Featured

Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM.

402957-28-2
DC10104 VX222(Lomibuvir) Featured

VCH-222(Lomibuvir) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L.

1026785-59-0
DC9751 Velpatasvir(GS5816) Featured

Velpatasvir(GS-5816) is a potent and selective Hepatitis C virus NS5A inhibitor.

1377049-84-7
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