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Cat. No. Product name CAS No.
DC10318 Acelarin(NUC1031) Featured

Acelarin (NUC-1031) is a ProTide transformation and enhancement of the widely-used nucleoside analogue, gemcitabine.

840506-29-8
DC5202 Luminespib (NVP-AUY922) Featured

AUY922 (NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Phase 1/2.

747412-49-3
DC10773 AZD5069

AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neutrophil migration into the airways in patients with COPD.

878385-84-3
DC4196 Bleomycin Sulfate

Bleomycin sulfate (Blenoxane) is a glycopeptide antibiotic and an anticancer agent for squamous cell carcinomas (SCC) with IC50 of 4 nM in UT-SCC-19A cells.

9041-93-4
DC8331 GSK2256098 Featured

GSK2256098 is small molecule FAK kinase inhibitor.

1224887-10-8
DC7429 INCB8761(PF-4136309) Featured

INCB8761(PF-4136309) is a potent, Selective, and orally bioavailable CCR2 antagonist.

1341224-83-6
DC7103 LY2603618(IC-83) Featured

LY2603618(IC-83) is a potent and selective small molecule inhibitor of Chk1 protein kinase activity in vitro (IC50=7 nM) and the first selective Chk1 inhibitor to enter clinical cancer trials.

911222-45-2
DC3122 MRK003

MRK003 is a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma.

623165-93-5
DC12276 Saridegib (IPI-926; Patidegib)

Saridegib is a potent and specific inhibitor of Smoothened (Smo), a key signaling transmembrane protein in the Hedgehog (Hh) pathway.

1037210-93-7
DC7689 Evofosfamide(TH-302) Featured

TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism.

918633-87-1
DC12037 Triptolide Featured

Triptolide is the major bioactive constituent of T. wilfordii Hook F., also known as thunder god vine, a traditional Chinese medicinal herb with known antiproliferative, immunosuppressive, anti-inflammatory, antifertility, and anti-polycystic kidney disea

38748-32-2
DC8272 U-104 Featured

U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM; low inhibition for CA I and CA II.

178606-66-1
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