Home > Inhibitors & Agonists > Nuclear Receptor/Transcription Factor > c-Myc
Cat. No. Product name CAS No.
DC7575 10058-F4 Featured

10058-F4 is a c-Myc inhibitor that specificallly inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression.

DC10075 10074-G5 Featured

10074-G5 is a c-Myc Max interaction inhibitor.

DC11918 CMLD010509

A rocaglate (flavagline) derivative that acts a highly specific inhibitor of the oncogenic translation program supporting MM, including key oncoproteins such as MYC, MDM2, CCND1, MAF, and MCL-1.

DC8664 APTO-253

APTO-253 is a novel small molecule with potent anti-tumor activity in cancer cells via induction of the gene that expresses the Krüppel-like factor 4 (KLF4) master transcription factor, leading to cell cycle inhibition and programmed cell death.

DC10617 CBL0137 Featured

CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-κB with an EC50 of 0.47 µM.

DC10952 MYCMI-6(NSC 354961) Featured

MYCMI-6 (NSC354961) is a selective, high affinity inhibitor of MYC-MAX interaction, blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with Kd of 1.6 uM in SPR assay.

DC10606 Mycro-3 Featured

Mycro 3 is potent and selective for c-Myc in whole cell assays.

DC11684 sAJM-589

sAJM-589 is a novel, potent small molecule Myc inhibitor that disrupts the Myc-Max leucine-zipper heterodimer with IC50 of 1.8 uM.

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