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Cat. No. Product name CAS No.
DC9137 Timolol Maleate

(S)-Timolol maleate, is a potent non-selective β-adrenergic receptor antagonist (Ki values are 1.97 and 2.0 nM for β1 and β2 receptor subtypes respectively).

26921-17-5
DCAPI1496 Ambrisentan

A nonpeptide endothelin ETA receptor antagonist. Antihypertensive.

177036-94-1
DC11547 LY-2562175

A novel potent, selective, partial FXR agonist with EC50 of 193 nM.

1103500-20-4
DC11893 Firibastat

A potent, orally active, centrally acting aminopeptidase inhibitor, the prodrug of the specific and selective aminopeptidase A inhibitor EC33.

648927-86-0
DC11850 MK-7145

A potent, selective, and oral renal outer medullary potassium channel (ROMK) inhibitor with IC50 of 68 nM.

1255204-84-2
DCAPI1468 Rosuvastatin Calcium

A selective, competitive inhibitor of HMG-CoA reductase, that is also antilipemic.

147098-20-2
DCAPI1495 Aliskiren Hemifumarate

Aliskiren hemifumarate(CGP 60536) is a direct renin inhibitor with IC50 of 1.5 nM.

173334-58-2
DC7804 Anacetrapib(MK0859)

Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3.

875446-37-0
DC5114 Apixaban (BMS 562247-01)

Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.

503612-47-3
DC9020 Atenolol

Atenolol is a selective β1 receptor antagonist.

29122-68-7
DCAPI1442 Atorvastatin Calcium

Atorvastatin Calcium

134523-03-8
DC1094 Avasimibe (CI-1011)

Avasimibe inhibits ACAT and CYP2C9 with IC50 of 3.3 μM and 2.9 μM, respectively.

166518-60-1
DC8004 AZD6482

AZD6482 is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ.

1173900-33-8
DC4210 Azilsartan kamedoxomil

Azilsartan medoxomil is an angiotensin II receptor antagonist indicated for the treatment of mild to moderate essential hypertension.

863031-24-7
DCAPI1469 azilsartan

Azilsartan(TAK-536) is a specific and potent angiotensin II type 1 receptor antagonist with IC50 of 2.6 nM.

147403-03-0
DC9596 Azimilide (Dihydrochloride)

Azimilide 2Hcl(NE-10064 2Hcl) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

149888-94-8
DC7782 BAY 41-2272

BAY 41-2272 is a soluble guanylate cyclase agonist, activates human mononuclear phagocytes

256376-24-6
DC7373 Betrixaban

Betrixaban (PRT-054021) is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM(inhibition of Factor 10a).

330942-05-7
DCAPI1112 BIBR 953(Dabigatran)

BIBR 953 (Dabigatran, Pradaxa) is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate.

211914-51-1
DC1010 BIBR-1048 (Dabigatran etexilate)

BIBR-1048 (Dabigatran) is an anticoagulant from the class of the direct thrombin inhibitors.

211915-06-9
DC9252 BMS-687453

BMS687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) α agonist, with an EC50 of 10 nM for human PPARα and ∼410-fold selectivity vs human PPARγ in PPAR-GAL4 transactivation assays.

1000998-59-3
DC9861 BMS-779788(XL-652)

BMS-779788(XL652) is a novel small-molecule modulator of the Liver X Receptor (LXR), a nuclear hormone receptor implicated in a variety of cardiovascular and metabolic disorders.

918348-67-1
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