Home > Inhibitors & Agonists > Immunology/Inflammation > STING
Cat. No. Product name CAS No.
DC12367 2'3'-cGAMP

2'3'-cGAMP has been used to identify small compounds capable of binding human stimulator of interferon genes (STING). It is also used to study type I interferon response to cytosolic DNA.

1441190-66-4
DC11641 Cridanimod

A potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.

38609-97-1
DC11642 Cridanimod sodium

Cridanimod sodium is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.

58880-43-6
DC12321 STING agonist-1(compound 3)trihydrochloride

diABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist.

2138299-34-8
DC10876 H-151

H-151(H151) is a novel STING (stimulator of interferon genes) antagonist.

941987-60-6
DC10908 ML RR-S2 CDA

ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING).

1638241-89-0
DC11072 SINCRO

SINCRO is a novel anti-cancer compound that can activate the cytosolic DNA-sensing STING signaling pathway leading to the induction of type I interferon (IFN) genes.

1494619-28-1
DC11451 STING agonist compound 3

STING agonist-3 is a novel STING agonist with even better activity than cGAMP.

2138299-33-7
DC11179 STING CDN agonist IFM Therapeutics

STING CDN agonist IFM Therapeutics is a synthetic cyclic dinucleotide (CDN) agonist of STING, stimulates potent immunity against cancer..

2197188-04-6
DC10960 STING inhibitor C-176

STING inhibitor C-178 is a covalent, in vivo-active, small-molecule inhibitor of STING

314054-00-7
DC10959 STING inhibitor C-178

STING inhibitor C-178 is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING; covalently binds to Cys91, directly targets mouse STING (mmSTING) but not human STING (hsSTING).

329198-87-0
DC28012 c-Di-AMP(Cyclic-Di-AMP) ammonium salt

Bis-(3'-5')-cyclic dimeric adenosine monophosphate (c-di-AMP) is a bacterial second messenger implicated in the control of cell wall metabolism, osmotic stress responses and sporulation. Detection of c-di-AMP by the host cytoplasmic surveillance pathway (CSP) is known to elicit type I IFN responses through a signaling axis that involves STING, TBK1 and IRF3 [1, 2]. Involvement of the helicase DDX41 in the recognition of c-di-AMP has been suggested [3]. Recent studies have also demonstrated that c-di-AMP exerts strong adjuvant activities when delivered by the mucosal route [4, 5].

54447-84-6
DC28013 Cyclic-di-GMP(c-di-GMP)

Cyclic di-GMP (c-di-GMP) is one of the most important and common bacterial second messenger. It is involved in numerous prokaryotic processes, including biofilm formation, motility, virulence, and cell cycling. c-di-GMP also has functions in eukaryotic cells. It is detected by the transmembrane protein stimulator of interferon genes (STING), leading to activation of the innate immune system.

61093-23-0
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