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Cat. No. Product name CAS No.
DC11518 Cavosonstat

A potent, orally bioavailable inhibitor of S-nitrosoglutathione reductase (GSNOR) and CFTR modulator.

1371587-51-7
DC9986 Acebilustat(ZK322) Featured

Acebilustat(ZK322) is a potent and selective leukotriene A4 hydrolase inhibitor.

943764-99-6
DC10459 BMS-986020 Featured

BMS-986020 is an LPA1 antagonist.

1257213-50-5
DC9278 CWHM-12 Featured

CWHM-12 a novel small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8; less potency on αvβ5(IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1.

1564286-55-0
DC9434 DMP 777

DMP 777(L-694458) is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor.

157341-41-8
DC11803 GLPG-1690(Ziritaxestat) Featured

GLPG-1690 is a first-in-class, potent, competitive autotaxin inhibitor with Ki/IC50 of 15 nM/131 nM.

1628260-79-6
DC10753 GLPG-1837(ABBV-974) Featured

GLPG-1837(ABBV-974) is a novel cystic fibrosis transmembrane conductance regulator CFTR potentiator.

1654725-02-6
DC11678 GLPG-2222

GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM.

1918143-53-9
DC4128 Ivacaftor (VX-770) Featured

Ivacaftor (VX-770, Kalydeco) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively.

873054-44-5
DC11096 Olacaftor

Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, showsthe potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis..

1897384-89-2
DC11100 PBI-4050 sodium

PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively.

1254472-97-3
DC11099 PBI-4050

PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively.

1002101-19-0
DC10390 TD139 Featured

TD139 is a novel high-affinity inhibitor of the galectin-3 carbohydrate binding domain with a Kd of 14 nM.

1450824-22-2
DC1059 Lumacaftor(vx-809,vx809) Featured

VX-809 is a CFTR modulator with EC50 of 0.1 μM.

936727-05-8
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