Home > PROTACs > E3 Ligase Ligand
Cat. No. Product name CAS No.
DC11578 VHL Ligand 3

A VHL ligand for PROTAC..

1448189-98-7
DC11581 VHL Ligand 4

A VHL ligand for PROTAC..

1631137-45-5
DC11580 VHL-2

A VHL ligand for PROTAC..

1631137-31-9
DC11588 CC-885

CC-885 (CC 885, CC885) is a novel E3 ligase cereblon (CRBN) modulator with potent anti-tumour activity mediated through the degradation of GSPT1.

1010100-07-8
DC12249 E3 ligase Ligand 1 dihydrochloride

E3 ligase Ligand 1 dihydrochloride is a Hippel-Landau (VHL) E3 ligase-binding moiety based on PROTAC technology.

DC22335 E3 ligase Ligand 1A Featured

E3 ligase Ligand 1A is a ligand of E3 ligase, used in PROTAC technology; E3 ligase Ligand 1A can be used in the research of cancer. (S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM[2].

1948273-02-6
DC11565 E3 Ligase Ligand 2

E3 ligase Ligand 2 is a Ligand for E3 Ligase used in PROTAC technology.

5054-59-1
DC11571 E3 Ligase Ligand 3 Featured

E3 ligase Ligand 3 is a ligand of E3 ligase, used in PROTAC technology.

1061605-21-7
DC12028 MDK7526(Protein degrader 1) Featured

MDK7526, also known as VHL Ligand 1; Protein degrader 1, is a potent and selective protein degrader.

1448189-80-7
DC11579 VH-032

VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM..

1448188-62-2
DC28693 Cereblon modulator 1

Cereblon modulator 1 (compound F) is a cereblon (CRBN) E3 ligase modulator. Cereblon modulator 1 specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex. This leads to the ubiquitination of certain substrate proteins and induces the proteasome-mediated degradation of certain transcription factors, including Ikaros (IKZF1) and Aiolos (IKZF3).

1860875-51-9
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