Home > Inhibitors & Agonists > Tyrosine Kinase > Focal Adhesion Kinase (FAK)
Cat. No. Product name CAS No.
DC8009 CEP-37440 Featured

CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).

1391712-60-9
DC7695 Defactinib (VS-6063, PF-04554878) Featured

Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel.

1073154-85-4
DC10100 Defactinib hydrochloride Featured

Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel.

1073160-26-5
DC8331 GSK2256098 Featured

GSK2256098 is small molecule FAK kinase inhibitor.

1224887-10-8
DC9787 NAMI-A

NAMI-A is a ruthenium anticancer agent and a metastasis inhibitor.

201653-76-1
DC4106 PF573228 Featured

PF 573228 is a inhibitor of FAK with IC50 of 4 nM.

869288-64-2
DC3168 PF-562271 PHSO3H SALT

PF-00562271 is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 of 1.5 nM and 14 nM, respectively.

939791-38-5
DC7941 PF-431396 Featured

PF-431396 is dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor , PF-431396 has a Kd value of 445 nM for BRD4.

717906-29-1
DC8526 PF4618433 Featured

PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796.

1166393-85-6
DC3169 PF-562271 Featured

PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 of 1.5 nM and 14 nM, respectively.

717907-75-0
DC7241 PND-1186 Featured

PND-1186 is a potent FAK inhibitor with IC50 of 1.5 nM.

1061353-68-1
DC7885 NVP-TAE226 Featured

TAE226 (NVP-TAE226) is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met.

761437-28-9
DC8376 TAS-301 Featured

TAS-301 is an inhibitor of smooth muscle cell migration and proliferation.

193620-69-8
DC9446 Y15

Y15 is a novel small molecule FAK phosphorylation inhibitor; specifically block phosphorylation of Y397-FAK and total phosphorylation of FAK.

4506-66-5
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