Home > Antibody Drug Conjugates
Cat. No. Product name CAS No.
DC8540 DM-1(Mertansine)

A cytotoxic agent used in antibody-drug conjugates

139504-50-0
DC11600 D211

A novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs).

1971075-99-6
DC8802 Maytansinol(Ansamitocin P-0)

Ansamitocin P-0

57103-68-1
DC8241 Ansamitocin P-3

Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29.

66547-09-9
DC11275 Calicheamicin

Calicheamicin is a potent DNA-damaging cytotoxic agent.

108212-75-5
DC9331 Daun02

Daun02 is a daunorubicin b-galactoside prodrug for use in conjunction.

290304-24-4
DC7069 Daunorubicin HCL

Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.

23541-50-6
DC8539 DM1-SMCC

DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate.

1228105-51-8
DC8703 Fmoc-Val-Cit-PAB

Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC).

159858-22-7
DC8701 Fmoc-Val-Cit-PAB-PNP

Fmoc-Val-Cit-PAB-PNP is a peptide prodrug linker, is a linker for antibody-drug-conjugation (ADC).

863971-53-3
DC10120 MC-Val-Cit-PAB

MC-Val-Cit-PAB, also known as MC-Val-Cit-PAB-OH, is a cathepsin cleavable ADC peptide linker. MC-Val-Cit-PAB is useful for making ADC conjugate (antibody-drug conjugate). FDA approved drugs such as brentuximab vedotin used this linker.

159857-80-4
DC8461 Mc-Val-Cit-PABC-PNP(VCMMAE linker)

Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker.

159857-81-5
DC10159 N3-PEG3-vc-PAB-MMAE

N3-PEG3-vc-PAB-MMAE is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the peptide N3-PEG3-vc-PAB.

DC7648 PNU159682

PNU-159682 is a major bioactive metabolite of Nemorubicin in human liver microsomes; > 3,000-fold cytotoxic than its parent compound(MMDX and doxorubicin).

202350-68-3
DC11012 SG3199

SG3199 is a PBD dimer warhead component of antibody-drug conjugate (ADC) payload tesirine, demonstrates potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines with mean GI50 of 151.5 pM.

1595275-71-0
DC11601 SGD-1882

SGD-1882 (PBD dimer, Pyrrolobenzodiazepine dimer) is a novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs)..

1222490-34-7
DC11013 Tesirine

Tesirine ( SG3249) is a cathepsin B-cleavable valine-alanine pyrrolobenzodiazepine (PBD) dimer as antibody-drug conjugate (ADC) payload.

1595275-62-9
DC7021 Monomethyl auristatin E (vedotin)

Monomethyl auristatin E (MMAE; Vedotin) is a hot topic in Antibody-drug conjugates (ADCs) studies. It is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin.

474645-27-7
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