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Cat. No. Product name CAS No.
DC12277 (-)-BAY-1251152

(-)-BAY-1251152 is an enanthiomer of BAY-1251152 with rotation (-). BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor.

1610358-59-2
DCZ-158 CALCIUML-5-METHYLTETRAHYDROFOLATE

>98%,Standard References

151533-22-1
DCK-004 corilagin

>98%,Standard References

23094-69-1
DC8567 3-(4-Pyridyl)

3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 µM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay

7272-84-6
DCAPI1525 5-Azacytidine

5-Azacytidine is a potent growth inhibitor and a cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. 5-Azacytidine also improves t

320-67-2
DC8944 5-Fluorouracil

5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.

51-21-8
DC11873 CDK12 inhibitor E9 R-isomer

A clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux.

2020052-51-9
DC11874 CDK12 inhibitor E9 racemate

A clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux.

2020052-41-7
DC11932 GPX-150

A doxorubicin analog that demonstrates anti-cancer activity without cardiotoxicity, does not inhibit topoisomerase IIβ activity at 100 uM.

236095-29-7
DC11779 TNKS-IN-41

A highly potent and selective tankyrase inhibitor with pIC50 of 8.5 and 8.1 for TNKS1 and TNKS2, respectively.

1584646-59-2
DC11718 Debromohymenialdisine

A marine sponge alkaloid that inhibits Chk1 and Chk2 with IC50 of 3 and 3.5 uM, respectively.

75593-17-8
DC11851 Clitocine

A naturally occurring nucleoside analog that possesses antitumor activity, also is a potent and efficacious readthrough agent.

105798-74-1
DC11863 CA224

A non-planar analogue of fascaplysin that selectively inhibits CDK4/cyclin D1 with IC50 of 5.5 uM.

883561-04-4
DC11888 Arfolitixorin

A novel antifolate modulator compound..

31690-11-6
DC11953 MU 380

A novel potent, selective CHK1 inhibitor 2 nM, >80-fold selectivity over CHK2.

2109805-78-7
DC11799 G1T38

A novel, potent and selective inhibitor of CDK4/6 with biochemical IC50 of 1 nM and 2 nM for CDK4/cyclin D1 and CDK6/cyclin D3, respectively.

1628256-23-4
DC11800 G1T38 dihydrochloride

A novel, potent and selective inhibitor of CDK4/6 with biochemical IC50 of 1 nM and 2 nM for CDK4/cyclin D1 and CDK6/cyclin D3, respectively.

2097938-59-3
DC11715 PV-1115

A potent and highly selective Chk2 inhibitor with IC50 of 0.14 nM.

1093793-10-2
DC11654 VRX-0466617

A potent and selective Chk2 inhibitor with Ki/IC50 of 11 nM/120 nM.

926906-64-1
DC11672 G-9791

A potent and selective group I PAK (pan-PAK1/2/3) inhibitor with Ki of 0.95/2 nM for PAK1/2, respectively.

1926204-95-6
DC11643 Olomoucine

A potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase.

101622-51-9
DC11714 PV-1019

A potent, ATP-competitive and highly selective Chk2 inhibitor with IC50 of 138 nM.

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