Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Monoacylglycerol Lipase (MAGL)
Cat. No. Product name CAS No.
DC11155 ABX-1431 Featured

ABX-1431 (ABX1431) is a highly potent, selective, orally available, CNS-penetrant monoacylglycerol lipase (MGLL) with IC50 of 14 nM (hMGLL).

1446817-84-0
DC11183 ABX-1431 hydrochloride Featured

ABX-1431 (ABX1431) is a highly potent, selective, orally available, CNS-penetrant monoacylglycerol lipase (MGLL) with IC50 of 14 nM (hMGLL).

2043074-64-0
DC11464 DO264 Featured

DO264 is a novel ABHD12 inhibitor.

DC10536 KML-29 Featured

KML29 is an O-hexafluoroisopropyl carbamate analog of JZL 184 that potently and selectively inhibits MAGL (IC50s = 15, 43, and 5.9 nM in mouse, rat, and human brain proteomes, respectively) over FAAH (IC50s >50 μM).

1380424-42-9
DC9990 URB602 Featured

URB602 is a selective inhibitor of monoglycerol lipase (MGL), exhibiting an IC50 of 28 µM for the rat brain enzyme.

565460-15-3
DC28746 JNJ-42226314

JNJ-42226314 is a competitive, highly selective and reversible non-covalent monoacylglycerol lipase (MAGL) inhibitor. JNJ-42226314 demonstrates dose-dependent enhancement of the major endocannabinoid 2-arachidonoylglycerol (2-AG) as well as efficacy in models of neuropathic and inflammatory pain.

1252765-13-1
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