Home > Inhibitors & Agonists > Tyrosine Kinase > c-Fms (CSF1R)
Cat. No. Product name CAS No.
DC12490 AZD7507

AZD7507 (AZD-7507) is a potent, selective, orally available CSF-1R (c-FMS) with IC50 of 32 nM.

DC8103 BLZ945

BLZ945 is a highly selective and brain-penetrant inhibitor of CSF1R with IC50 of 1 nM; >3200-fold higher than its affinity for other kinases.

DC11398 Edicotinib(JNJ-40346527)

Edicotinib(JNJ-40346527)is a small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; FMS) with potential antineoplastic activity.

DC1018 GW-2580 (GW2580)

GW2580 is a selective inhibitor of human c-FMS with IC50 of 30 nM.

DC7438 JNJ-28312141

JNJ-28312141 is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and also a FLT3 inhibitor.

DC7168 Ki20227

Ki-20227 is a highly selective c-Fms tyrosine kinase(CSF1R) inhibitor with IC50 value of 2 nM; 6 fold and > 100 fold selectivity over VEGFR2(IC50=12 nM) and c-Kit/PDGFR_beta_(IC50=451/217 nM), respectively.

DC8158 Pexidartinib(PLX3397)

PLX3397 is a tyrosine kinase inhibitor that potently inhibits the colony stimulating factor 1 (CSF1) receptor kinase, a driving force in the development and growth of PVNS.

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