Home > Inhibitors & Agonists > Tyrosine Kinase > c-Fms (CSF1R)
Cat. No. Product name CAS No.
DC12490 AZD7507

AZD7507 (AZD-7507) is a potent, selective, orally available CSF-1R (c-FMS) with IC50 of 32 nM.

1041852-85-0
DC8103 BLZ945 Featured

BLZ945 is a highly selective and brain-penetrant inhibitor of CSF1R with IC50 of 1 nM; >3200-fold higher than its affinity for other kinases.

953769-46-5
DC11398 Edicotinib(JNJ-40346527) Featured

Edicotinib(JNJ-40346527)is a small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; FMS) with potential antineoplastic activity.

1142363-52-7
DC1018 GW-2580 (GW2580) Featured

GW2580 is a selective inhibitor of human c-FMS with IC50 of 30 nM.

870483-87-7
DC7438 JNJ-28312141

JNJ-28312141 is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and also a FLT3 inhibitor.

885692-52-4
DC7168 Ki20227 Featured

Ki-20227 is a highly selective c-Fms tyrosine kinase(CSF1R) inhibitor with IC50 value of 2 nM; 6 fold and > 100 fold selectivity over VEGFR2(IC50=12 nM) and c-Kit/PDGFR_beta_(IC50=451/217 nM), respectively.

623142-96-1
DC8158 Pexidartinib(PLX3397) Featured

PLX3397 is a tyrosine kinase inhibitor that potently inhibits the colony stimulating factor 1 (CSF1) receptor kinase, a driving force in the development and growth of PVNS.

1029044-16-3
DC28328 PLX5622 hemifumarate

PLX5622 hemifumarate is a highly selective brain penetrant and oral active CSF1R inhibitor with an Ki of 5.9 nM, for extended and specific microglial elimination, preceding and during pathology development. PLX5622 hemifumarate demonstrates desirable PK properties in varies animals.

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