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Cat. No. Product name CAS No.
DC11019 ASP3662

ASP3662 is a potent, selective, CNS-penetrable and orally active inhibitor of 11β-HSD1 with Ki of 5.3, 2.6 and 23 nM for human, mouse and rat 11β-HSD1, does not inhibit human 11β-HSD2 at 30 uM.

1204178-50-6
DC11206 HSD-016

HSD-016 (HSD016) is a potent, selective, and efficacious 11β-HSD1 inhibitor with IC50 of 149 and 530 nM for mouse and human 11β-HSD1, respectively.

946396-92-5
DC11207 INCB13739

INCB13739 (INCB-13739) is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) with high seelctivity over other dehydrogenases, glucocorticoid and mineralocorticoid receptors..

872506-67-7
DC11205 INU-101

INU-101 (INU101) is a highly potent, selective, orally acitve 11β-HSD1 inhibitor with IC50 of 26.2 nM, 37 nM and 0.6 nM for mice, rats, and human 11β-HSD1, respectively.

1513828-41-5
DC9584 (R)-(-)-Rolipram

(R)-(-)-Rolipram is a potent and cAMP-specific PDE4 inhibitor with IC50 of 0.22 uM; 2.5-fold more potent than (+)-rolipram (IC50= 2.58 uM) in inhibiting membrane-bound PDE 4.

85416-75-7
DC9581 (S)-(+)-Rolipram

(S)-(+)-Rolipram is a PDE4-inhibitor and an anti-inflammatory agent, less potent than its R enantiomer.

85416-73-5
DCS-019 (-)-Huperzine A

>98%,Standard References

102518-79-6
DC10014 2-PMPA(NAALADaseinhibitor)

2-PMPA is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM.

173039-10-6
DC7038 A 922500

A 922500 is a potent, selective, and orally bioavailable DGAT-1 inhibitor with IC50 values of 7 nM and 24 nM for human and mouse DGAT-1 respectively.

959122-11-3
DC11538 AD-35

A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates.

1531586-58-9
DC11539 AD-35 hydrochloride

A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates.

1531586-62-5
DC11537 AD-35 phosphate

A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates.

1531586-64-7
DC11936 TAK-915

A highly potent, selective, brain-penetrating and orally active phosphodiesterase 2A (PDE2A) inhibitor with IC50 of 0.61 nM.

1476727-50-0
DC11522 Imarikiren hydrochloride

A highly potent, selective, orally active renin inhibitor with IC50 of 2.1 nM in hPRA assay.

1202269-24-6
DC11663 GS-5759

A novel bifunctional PDE4 inhibitor (IC50=5 nM) and long acting β2-adrenoceptor agonist (EC50=8 nM).

1346653-91-5
DC11995 BI 703704

A novel potent soluble guanylate cyclase (sGC) activator.

1423067-48-4
DC11693 AJS1669 sodium

A novel potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM.

DC11692 AJS1669

A novel potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM.

1853130-05-8
DC11904 Olinciguat

A novel potent, selective guanylate cyclase activator for the treatment of nonalcoholic steatohepatitis (NASH)..

1628732-62-6
DC11559 PDE5-IN-6c

A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1.

1448419-13-3
DC11969 (S)-C33

A novel potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms.

2066488-39-7
DC11777 PDM-631

A novel potent, selective, brain-penetrable and orally active PDE2A inhibitor with IC50 of 1.5 and 4.2 nM for human and rat PDE2A, respectively.

2095312-08-4
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