Home > Inhibitors & Agonists
Cat. No. Product name CAS No.
DC8086 Moclobemide Featured

Moclobemide belongs to a new generation of short-acting, reversible, monoamine oxidase (MAO) inhibitors.

71320-77-9
DCAP008 QS-21

>98%,Standard References

141256-04-4
DC7524 Uramustine

Uramustine (INN), also known as uracil mustard, is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells. Bone marrow suppression and nausea are the main side effects. Chemically it is a derivative of nitrogen mustard and uracil.For the detailed information of Uramustine, the solubility of Uramustine in water, the solubility of Uramustine in DMSO, the solubility of Uramustine in PBS buffer, the animal experiment (test) of Uramustine, the cell expriment (test) of Uramustine, the in vivo, in vitro and clinical trial test of Uramustine, the EC50, IC50,and Affinity of Uramustine, Please contact DC Chemicals..

66-75-1
DC11019 ASP3662

ASP3662 is a potent, selective, CNS-penetrable and orally active inhibitor of 11β-HSD1 with Ki of 5.3, 2.6 and 23 nM for human, mouse and rat 11β-HSD1, does not inhibit human 11β-HSD2 at 30 uM.

1204178-50-6
DC11206 HSD-016

HSD-016 (HSD016) is a potent, selective, and efficacious 11β-HSD1 inhibitor with IC50 of 149 and 530 nM for mouse and human 11β-HSD1, respectively.

946396-92-5
DC11207 INCB13739

INCB13739 (INCB-13739) is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) with high seelctivity over other dehydrogenases, glucocorticoid and mineralocorticoid receptors..

872506-67-7
DC11205 INU-101

INU-101 (INU101) is a highly potent, selective, orally acitve 11β-HSD1 inhibitor with IC50 of 26.2 nM, 37 nM and 0.6 nM for mice, rats, and human 11β-HSD1, respectively.

1513828-41-5
DC20787 (-) BI97D6

(-) BI97D6 (BI112D1) is a potent, pan-active inhibitor of Bcl-2 family proteins with IC50 of 76, 31, 25, and 122 nM for Bcl-xL, Bcl-2, Mcl-1, and Bfl-1, respectively.

1256724-10-3
DC12277 (-)-BAY-1251152

(-)-BAY-1251152 is an enanthiomer of BAY-1251152 with rotation (-). BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor.

1610358-59-2
DC7818 (-)Blebbistatin

(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.

856925-71-8
DC20288 (-)-CXL017

(-)-CXL017 is a small molecule that has selective cytotoxicity toward MDR cancer cell lines in vitro, through inhibition of the sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) with IC50 of 13.5 uM.

1318166-37-8
DC22303 (-)-Eburnamonine Featured

(-)-Eburnamonine is a vasodilator that also acts as a cerebral metabolic stimulant.

4880-88-0
DC7961 (-)MK-801 maleate Featured

(-)-MK 801 Maleate is the enantiomer of (+)-MK-801; (+)-MK-801 is a highly potent and selective non-competitive NMDA glutamate receptor antagonist .

121917-57-5
DC9624 (-)-Sparteine (sulfate pentahydrate)

(-)-Sparteine sulfate pentahydrate is a class 1a antiarrhythmic agent and a sodium channel blocker.

6160-12-9
DC10625 (+)-Bicuculline Featured

(+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels.

485-49-4
DC10656 (+)-JQ1 carboxylic acid Featured

(+)-JQ1 carboxylic acid is the carboxylic acid form of (+)-JQ1 for derivative synthesis.

202592-23-2
DC5019 (+)-JQ1 Featured

(+)-JQ1 is a BET bromodomain inhibitor, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family.

1268524-70-4
DC12021 (+)-JQ1 PA Featured

(+)-JQ1 PA is a Click-activated (alkyne) version of the BET bromodomain inhibitor (+)-JQ1.

2115701-93-2
DC20149 (+)-Kavain

(+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels. (+)-Kavain is shown to bind at the α4β2δ GABA

500-64-1
DC11321 (+)-Muscarine (chloride)

(+)-Muscarine is an agonist of muscarinic acetylcholine receptors that was originally found in A. muscaria.

2303-35-7
DC5060 (+)PD 128907

(+)PD 128907 is a potent D3 dopamine receptor agonist (Ki = 2.3 nM). Displays 18 - 200-fold selectivity over other dopamine receptor subtypes.

300576-59-4
DC20138 (+)-Penbutolol ((R)-Penbutolol; (+)-Isopenbutolol)

(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action.

38363-41-6
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