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Cat. No. Product name CAS No.
DC11758 PB 28 dihydrochloride

A potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively.

172907-03-8
DC11757 PB 28

A potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively.

172906-90-0
DC11545 IPAG

A prototypic selective inhibitor of sigma1 receptor that engages the unfolded protein response and induces autophagy in cancer cells.

193527-91-2
DC8313 BD1047.2HBr Featured

BD 1047 dihydrobromide is a selective antagonist of σ receptors.

138356-21-5
DC10280 BD1063 dhydrochloride Featured

BD1063 dhydrochloride is a potent and selective sigma 1 receptor antagonist.

206996-13-6
DC10954 BS148

BS148 (BS-148) is a potent, selective σ2 receptor agonist with pKi of 7.71, displays 25-fold selectivity over σ1.

2162116-09-6
DC10455 NE-100 Featured

NE100 hydrochloride is a potent and selective σ1 receptor antagonist (Ki = 0.86 nM) that displays > 55-fold selectivity over σ2 receptors and > 6000-fold selectivity over D1,

149409-57-4
DC8347 PRE-084 hydrochloride Featured

PRE-084 hydrochloride is a high affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively).

138847-85-5
DC7274 S1RA Featured

S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM).

878141-96-9
DC9264 S1RA hydrochloride Featured

S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM).

1265917-14-3
DC28360 (2R,3S)-E1R

(2R,3S)-E1R (Compound 2c) is an enantiomer of E1R. (2R,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders.

1424832-60-9
DC28361 (2S,3S)-E1R

(2S,3S)-E1R (Compound 2d) is an enantiomer of E1R. (2S,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders.

1424832-57-4
DC28362 (2R,3R)-E1R

(2R,3R)-E1R (Compound 2b) is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders.

1400888-63-2
DC28363 (Rac)-E1R

(Rac)-E1R (Compound 2) is the racemate of E1R. (Rac)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders.

787623-60-3
DC28961 SR-31747

SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase.

132173-07-0
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