Home > Inhibitors & Agonists > Nuclear Receptor/Transcription Factor > Farnesoid X Receptor (FXR)
Cat. No. Product name CAS No.
DCE-016 Chenodeoxycholic acid

>98%,Standard References

474-25-9
DC11547 LY-2562175

A novel potent, selective, partial FXR agonist with EC50 of 193 nM.

1103500-20-4
DC10868 Cilofexor

Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.

1418274-28-8
DC8069 Fexaramate

Fexaramate is a potent, selective farnesoid X receptor agonist.

592524-75-9
DC8085 Fexaramine

Fexaramine is a potent, selective FXR activator.

574013-66-4
DC8070 Fexarene

Fexarene is a potent, selective farnesoid X receptor agonist.

574013-68-6
DC8071 Fexarine

Fexarine is a potent, selective farnesoid X receptor agonist.

574013-67-5
DC7566 GW-4064

GW 4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).

278779-30-9
DC7430 Obeticholic acid (INT-747)

INT-747(Obeticholic acid; 6-ECDCA) is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity.

459789-99-2
DC10470 SB756050

SB-756050 is a Farnesoid X receptor (FXR) (NR1H4) agonist.

447410-57-3
DC10737 Tropifexor (LJN452)

Tropifexor (LJN452) is a highly potent non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).

1383816-29-2
DC7040 WAY-362450 (XL335; Turofexorate isopropyl)

WAY-362450 (XL335; Turofexorate isopropyl) is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist with an EC50 of 4 nM.WAY-362450 is useful for dyslipidemia.

629664-81-9
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