Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Beta-secretase (BACE)
Cat. No. Product name CAS No.
DC11889 Atabecestat

Atabecestat (JNJ-54861911, JNJ54861911) is a novel potent, oral beta-secretase (BACE) inhibitor for treatment of Alzheimer's Disease.

1200493-78-2
DC9946 Lanabecestat(AZD3293,LY-3314814)

AZD3293 is a potent and selective orally active, brain-permeable BACE1 inhibitor,currently in development as a potential treatment for early Alzheimer’s disease.

1383982-64-6
DC8400 AZD3839

AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.

1227163-84-9
DC11105 Umibecestat

beta-secretase inhibitor.

1387560-01-1
DC11551 Elenbecestat

Elenbecestat (E2609) is a novel potent, oral BACE1 inhibitor for treatment of Alzheimer's disease..

1388149-39-0
DC5180 LY2811376

LY2811376 is the first orally available non-peptidicβ-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM.

1194044-20-6
DC5053 LY2886721

LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.

1262036-50-9
DC9901 Verubecestat (MK-8931)

MK-8931 is a BACE1 inhibitor. MK-8931 binds significantly to β-secretase.

1286770-55-5
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