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Cat. No. Product name CAS No.
DC9584 (R)-(-)-Rolipram

(R)-(-)-Rolipram is a potent and cAMP-specific PDE4 inhibitor with IC50 of 0.22 uM; 2.5-fold more potent than (+)-rolipram (IC50= 2.58 uM) in inhibiting membrane-bound PDE 4.

85416-75-7
DCAPI1409 Maxacalcitol

22-Oxacalcitriol is a Vitamin D3 analog which is Non-calcemic as well as a VDR ligand. 22-Oxacalcitriol has been shown to decrease parathyroid hormone (PTH) mRNA expression in vitro. Additionally has been noted to exhibit similar effects to calcitriol in

103909-75-7
DC11530 Benvitimod Featured

A natural aryl hydrocarbon receptor (AhR) agonist with anti-inflammatory properties.

79338-84-4
DC11910 IPL-576092

A novel orally active, anti-inflammatory compound that inhibits leukocyte infiltration and changes in lung function in response to allergen challenge.

202415-99-4
DC11868 Freselestat

A potent, selective and orally active human neutrophil elastase (HNE) inhibitor with Ki of 12 nM.

208848-19-5
DC10417 Acumapimod

Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 μM for p38α.

836683-15-9
DC11886 Adavivint Featured

Adavivint (SM-04690, SM 04690, SM04690) is a novel small molecule Wnt pathway inhibitor with EC50 of 3 nM in vitro

1467093-03-3
DC11097 ADX-102

ADX-102 (Reproxalap, NS-2) is a novel small molecule immunomodulator that covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal, which have been shown to mediate inflammatory pain.

916056-79-6
DCAPI1467 Alcaftadine

Alcaftadine

147084-10-4
DC9406 Ampiroxicam

Ampiroxicam(CP65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.

99464-64-9
DC7815 Crisaborole(AN-2728) Featured

AN-2728 is a topically administered, boron-containing, anti-inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines.

906673-24-3
DC7063 Apremilast Featured

Apremilast(CC10004) is a novel small molecule inhibitor of PDE4 with an IC50 value of 74 nM.

608141-41-9
DC5014 AVL-292 Featured

AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Btk currently being evaluated in a Phase 1b clinical trial in relapsed.

1202757-89-8
DC11802 AX-024 free base

AX-024 is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.

1370544-73-2
DC10545 AX-024 HCl Featured

AX-024 is the first-in-class inhibitor of T cell receptor (TCR); AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM).

1704801-24-0
DC10724 AZD2098 Featured

AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor, used for asthma research.

566203-88-1
DC11723 AZD-7986

AZD-7986(INS-1007, AZD7986) is a highly potent, reversible, and selective DPP1 inhibitor with enzyme and cell pIC50 of 8.4.

1802148-05-5
DC10425 AZD9056 hydrochloride

AZD9056 is a selective orally active inhibitor of P2X7 which plays a significant role in inflammation and pain-causing diseases.

345303-91-5
DC11541 AZD-9567

AZD-9567 (AZD9567) is a potent, selective, non-steroidal and orally available selective glucocorticoid receptor modulator (SGRM) for treatment of rheumatoid arthritis..

1893415-00-3
DC11542 AZD-9567 monohydrate

AZD-9567 (AZD9567) is a potent, selective, non-steroidal and orally available selective glucocorticoid receptor modulator (SGRM) for treatment of rheumatoid arthritis..

1893415-64-9
DC9117 Bambuterol HCl

Bambuterol Hcl is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.

81732-46-9
DC10021 Batefenterol Featured

Batefenterol(GSK961081,TD-5959)is a Muscarinic Antagonist and β2-Agonist possessing both muscarinic antagonist (MA) and β2-adrenoceptor agonist (BA) properties (MABA).

743461-65-6
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