Home > Inhibitors & Agonists > GPCR > Lysophospholipid Receptor
Cat. No. Product name CAS No.
DC11605 ONO-0300302

A novel potent, slow tight binding LPA1 receptor antagonist with IC50 of 86 nM, Kd of 0.34 nM.

856689-51-5
DC11560 SPM-242

A potent, selective S1P3 antagonist with Ki of 0.25 nM.

DC11561 SPM-242 racemate

A potent, selective S1P3 antagonist with Ki of 0.25 nM.

749263-43-2
DC11525 Mocravimod

A synthetic immunosuppressant that functions as a S1P1 receptor agonist.

509092-16-4
DC11754 AD 2900

AD 2900 (AD2900, AD-2900) is a novel potent, broad S1P receptor antagonist with IC50 of 3.8, 3.2, 6.2, 5.9 and 0.405 uM for S1P1, 2, 3, 4 and 5 respectively.

18360-29-7
DC8621 AM095

AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.

1345614-59-6
DC8622 AM095 free acid

AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.

1228690-36-5
DC8623 AM966

AM966 is a high affinity, selective, oral LPA1 (lysophosphatidic acid receptor, IC50=17 nM) antagonist, with selectivity for this receptor over the other LPA receptors.

1228690-19-4
DC10459 BMS-986020 Featured

BMS-986020 is an LPA1 antagonist.

1257213-50-5
DC10924 BMS-986202

BMS-986202 (BMS-986202, AM-152) is a potent, selective, orally available antagonist of the Lysophosphatidic Acid 1 Receptor (LPA1 receptor) with IC50 of 18 and 9 nM in calcium mobilisation and β-arrestin assays.

DC10357 Cenerimod

Cenerimod (ACT-334441) is a potent and orally available sphingosine 1-phosphate 1 receptor (S1P1) agonist extracted from patent WO 2016184939 A1 and WO 2011007324 A1, example 1, with an EC50 of 2.7 nM.

1262414-04-9
DC8088 CYM5442 Featured

CYM-5442 is a highly-selective S1P1 (Spingosine 1-Phosphate Receptor 1) agonist.

1094042-01-9
DC10040 Etrasimod(APD334) Featured

Etrasimod (APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1(S1P1) receptor with an IC50 value of 1.88 nM in CHO cells.

1206123-37-6
DC8936 Fingolimod

Fingolimod(FTY720 free base) is a S1P antagonist with IC50 of 0.033 nM.

162359-55-9
DC8889 Ki16198 Featured

Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6.

355025-13-7
DC7179 Ki16425 Featured

Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively, shows no activity at LPA4, LPA5, LPA6.

355025-24-0
DC10630 ONO-7300243

ONO-7300243 is a novel, potent LPA1(Lysophosphatidic Acid Receptor) antagonist with an IC50 of 160 nM.

638132-34-0
DC8281 Ozanimod (RPC1063) Featured

Ozanimod (RPC1063) is a selective S1P1R modulator

1306760-87-1
DC9742 Ponesimod Featured

Ponesimod(ACT-128800) is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM.

854107-55-4
DC10392 S1p receptor agonist 1

S1p receptor agonist 1 is an S1P receptor agonist extracted from patent WO 2015039587 A1, compound example 2.

1514888-56-2
DC10925 SAR-100842

SAR-100842 (SAR100842) is a potent, selective, orally available antagonist of the Lysophosphatidic Acid 1 Receptor (LPA1 receptor) with IC50 of 31 nM in β-arrestin assays.

1195941-38-8
DC7295 SphK-I2 Featured

SKI II is a highly selective and non ATP-competitive S1P receptor inhibitor with IC50 of 0.5 μM, while exhibits no inhibitory on other kinases including PI3K, PKCα and ERK2.

312636-16-1
Page 1 / Total 2 FirstPrevNextLastGoto