Home > Inhibitors & Agonists > Cell Cycle/DNA Damage > Antifolate
Cat. No. Product name CAS No.
DCZ-158 CALCIUML-5-METHYLTETRAHYDROFOLATE

>98%,Standard References

151533-22-1
DC11888 Arfolitixorin

A novel antifolate modulator compound..

31690-11-6
DC8149 Pemetrexed disodium Featured

Pemetrexed disodium is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.

150399-23-8
DC9359 Pralatrexate Featured

Pralatrexate(Folotyn) is an antifolate, and structurally a folate analog.

146464-95-1
DC28970 Aminopterin

Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia.

54-62-6
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