Home > Inhibitors & Agonists > Cytoskeleton/Cell Adhesion Molecules
Cat. No. Product name CAS No.
DC7818 (-)Blebbistatin

(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.

856925-71-8
DCS-091 Cephalomannine

>98%,Standard References

71610-00-9
DCC-002 Vinblastine

>98%,Standard References

865-21-4
DCQ-004 4'-Demethylepipodophyllotoxin

>98%,Standard References

6559-91-7
DC11928 MPT0B002

A novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells.

946077-08-3
DC11935 PBOX-15

A novel microtubule targeting agent that induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple cancer cells.

354759-10-7
DC11636 HMCEF

A novel P-selectin inhibitor that directly binds to P-selectin.

2002363-68-8
DC11694 STK899704

A novel tubulin inhibitor that inhibits the proliferation of cancer cell lines with IC50 of 0.2-1.0 uM.

1578247-29-6
DC7353 ABT-751(E 7010) Featured

ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively.

141430-65-1
DC9487 Arg-Gly-Asp-Ser

Arg-Gly-Asp-Ser(RGDS peptide) is an integrin binding sequence that inhibits integrin receptor function; decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS

91037-65-9
DC12274 AZ82

AZ82 is a selective HSET/KIFC1 inhibitor, with a Ki of 43 nM and an IC50 of 300 nM for KIFC1.

1449578-65-7
DC11178 BIO1211

BIO1211 (BIO-1211) is a potent, highly specific integrin α4β1 (VLA-4) inhibitor with Kd/IC50 of 20 pM/4 nM for the activated form of α4β1.

187735-94-0
DC4186 Cabazitaxel

Cabazitaxel (Jevtana, XRP6258) is a semi-synthetic derivative of a natural taxoid.

183133-96-2
DC7386 CK-636 Featured

CK-636(CK-0944636) is a small molecule inhibitor of Arp2/3 complex; Inhibitor of actin polymerization; Cell permeable inhibitor of human (IC50=4μM), fission yeast (IC50=24μM) and bovine (IC50=32μM) Arp2/3 complex between Arp2 and Arp3.

442632-72-6
DC11475 CK-869 Featured

CK-869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex.

388592-44-7
DC11107 CKD-516

CKD-516 (Valecobulin, CKD516) is a potent beta-tubulin polymerization inhibitor with marked antitumor activity both in vitro and in vivo.

1188371-47-2
DC9278 CWHM-12 Featured

CWHM-12 a novel small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8; less potency on αvβ5(IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1.

1564286-55-0
DC8055 cyclo(-RGDfK) Featured

cyclo(-RGDfK,-Arg-Gly-Asp-D-Phe-Lys)) is a selective αvβ3-integrin antagonist.

161552-03-0
DC8399 Cyclo(RGDyK) Featured

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.

250612-42-1
DC5134 lexibulin (CYT997)

CYT997 is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines. Phase 1/2.

917111-44-5
DC10919 DRP1 inhibitor 4

DRP1 inhibitor 4 is a selective, small molecule inhibitor of the mammalian mitochondrial division dynamin, DRP1 with IC50 of 1.0 uM, shows no activity against OPA1 and DYN1 (IC50>100 uM)..

DC11177 DS-70

DS-70 (α4 integrin inhibitor DS-70) is a novel potent α/β- peptidomimetic antagonist of α4 integrin, binds to integrin α4β1 with nanomolar affinity.

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