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Cat. No. Product name CAS No.
DC11868 Freselestat

A potent, selective and orally active human neutrophil elastase (HNE) inhibitor with Ki of 12 nM.

208848-19-5
DC10417 Acumapimod

Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 μM for p38α.

836683-15-9
DC11723 AZD-7986

AZD-7986(INS-1007, AZD7986) is a highly potent, reversible, and selective DPP1 inhibitor with enzyme and cell pIC50 of 8.4.

1802148-05-5
DC10021 Batefenterol Featured

Batefenterol(GSK961081,TD-5959)is a Muscarinic Antagonist and β2-Agonist possessing both muscarinic antagonist (MA) and β2-adrenoceptor agonist (BA) properties (MABA).

743461-65-6
DC11859 BAY85-8501

BAY 85-8501 (BAY85-8501) is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 65 pM.

1161921-82-9
DC9582 Cilomilast

Cilomilast(SB 207499; Ariflo) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity.

153259-65-5
DC9689 Danirixin (GSK1325756) Featured

Danirixin(GSK1325756) is a selective CXCR2 antagonist.

954126-98-8
DC8779 Glycopyrrolate

Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.

596-51-0
DC9943 PI3Kδ inhibitor GS2269557

GSK-2269557 is a potent and selective PI3Kδ inhibitor over the closely related isoforms.

1254036-71-9
DC9944 PI3Kδ inhibitor GS2292767

GSK2292767 is a potent and selective PI3Kδ inhibitor.

1254036-66-2
DC8767 GSK256066 Featured

GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.

801312-28-7
DC10384 Olodaterol Featured

Olodaterol (BI1744) is a long acting β2-adrenoceptor agonist with an EC50 of 1.4±0.08 nM.

868049-49-4
DC9248 Olodaterol(BI-1744) hydrochloride Featured

Olodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in the lungs.

869477-96-3
DC9410 SCH 527123

SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively.

473727-83-2
DC8813 TD-4208 Featured

TD-4208 is a potent and selective inhaled muscarinic antagonist with functional lung selectivity and long duration of action in preclinical models of bronchoconstriction.

864750-70-9
DC7516 TG100-115 Featured

TG100115 is a PI3Kγ/δ inhibitor with IC50 of 83 nM/235 nM, with little effect on PI3Kα/β. Phase 1/2.

677297-51-7
DCAPI1449 Tiotropium Bromide Featured

Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR M) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. This stops signaling between neurons and leads to muscle relaxation.

136310-93-5
DC8153 Umeclidinium bromide Featured

Umeclidinium bromide(GSK573719A) is a muscarinic receptor antagonist which is useful in treatment of chronic obstructive pulmonary disease (COPD).

869113-09-7
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