Home > Inhibitors & Agonists > PI3K/Akt/mTOR > mTOR
Cat. No. Product name CAS No.
DC11929 ME-344

A novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM.

1374524-68-1
DC11866 AZD 3147

A potent, selective dual mTORC1 and mTORC2 inhibitor with enzyme IC50 of 1.5 nM.

1101810-02-9
DC1001 FK-506 (Tacrolimus) Featured

An immunosuppressive agent and macrolide antibiotic.

104987-11-3
DC5084 AZD-8055 Featured

AZD-8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.

1009298-09-2
DC8377 CC-115 Featured

CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with potential antineoplastic activity.

1228013-15-7
DC8497 CC-223 Featured

CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity over the related lipid kinase PI3Kα (IC50=4 μM).

1228013-30-6
DC10125 CZ415 Featured

CZ415 is a potent and highly selective mTOR inhibitor.

1429639-50-8
DC1501 Everolimus Featured

Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM.

159351-69-6
DC7014 GPI-1046

For the detailed information of GPI-1046, the solubility of GPI-1046 in water, the solubility of GPI-1046 in DMSO, the solubility of GPI-1046 in PBS buffer, the animal experiment (test) of GPI-1046, the cell expriment (test) of GPI-1046, the in vivo, in vitro and clinical trial test of GPI-1046, the EC50, IC50,and Affinity of GPI-1046, Please contact DC Chemicals..

186452-09-5
DC11151 ICSN3250 hydrochloride

ICSN3250 (ICSN-3250) hydrochloride is a halitulin-analogue that acts as a new-class, specific mTOR inhibitor through a mechanism distinct from previous mTOR inhibitors.

1561902-79-1
DC11150 ICSN3250

ICSN3250 (ICSN-3250) is a halitulin-analogue that acts as a new-class, specific mTOR inhibitor through a mechanism distinct from previous mTOR inhibitors.

1561902-73-5
DC7171 INK-128 Featured

INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less potent to class I PI3K isoforms.

1224844-38-5
DC3101 Ku-0063794

KU-0063794 is a potent and highly specific mTOR inhibitor for both mTORC1 and mTORC2 with IC50 ~10 nM.

938440-64-3
DC7210 LY-303511

LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit PI3-K.

154447-38-8
DC1006 OSI-027

OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively.

936890-98-1
DC7482 Torkinib (PP242) Featured

PP242 is a selective mTOR inhibitor with IC50 of 8 nM; targets both mTOR complexes with >10- and 100-fold selectivity for mTOR than PI3Kδ or PI3Kα/β/γ, respectively; also showed slightly weaker activity against BRD4 (Kd= 1.7 uM).

1092351-67-1
DC11816 RapaLink-1

RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors.

1887095-82-0
DC1048 Rapamycin (Sirolimus) Featured

Rapamycin (Sirolimus, AY-22989, WY-090217) is a specific mTOR inhibitor with IC50 of ~0.1 nM. -

53123-88-9
DC11306 Secorapamycin A(Seco Rapamycin) Featured

Seco-rapamycin(Secorapamycin A) is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR..

147438-27-5
DCAPI1488 Temsirolimus Featured

Temsirolimus is an inhibitor of ribosomal protein S6 phosphorylation and inhibits cell growth and clonogenic survival of cells in a concentration-dependent manner.

162635-04-3
DC3117 Torin2 Featured

Torin 2 is a highly potent and selective mTOR inhibitor with IC50 of 0.25 nM, and also exhibits potent cellular activity against ATM/ATR/DNA-PK with EC50 of 28 nM, 35 nM and 118 nM, respectively.

1223001-51-1
DC3118 Torin1 Featured

Torin1 is a potent inhibitor of mTOR with IC50 of 2-10 nM.

1222998-36-8
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