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SM6.1 (αvβ6 ligand)

Cat. No.: DC67297 Featured

Chemical Structure

2320477-40-3

For research use only. We do not sell to patients.

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Field of application

SM-6.1 is a small molecule delivery vehicle developed by Arrowhead, targeting αvβ6, which selectively delivers therapeutic siRNA to lung epithelial cells and mediates durable gene silencing post-inhalation.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	2320477-40-3
Chemical Name:	SM6.1 (αvβ6 ligand)
SMILES:	CC1=CC(NCCCC(=O)NCC(=O)N[C@H](CC(=O)O)C2=CC=C(C3=CC=C(OCCOCCOCCOCCOCCN=[N+]=[N-])C4=CC=CC=C34)C=C2)=NC=C1
Formula:	C₄₁H₅₁N₇O₉
M.Wt:	785.90 Da
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC67297	SM6.1 (αvβ6 ligand)	SM-6.1 is a small molecule delivery vehicle developed by Arrowhead, targeting αvβ6, which selectively delivers therapeutic siRNA to lung epithelial cells and mediates durable gene silencing post-inhalation.
DC80412	Tri-SM6.1	Tri-SM6.1 is a tridentate small-molecule ligand targeting integrin αvβ6. Tri-SM6.1 binds to integrin αvβ6 on epithelial cells to deliver conjugated α-ENaC RNAi agents。

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.