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Diroximel Fumarete(ALKS-8700)

  Cat. No.:  DC10582   Featured
Chemical Structure
1577222-14-0
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Field of application
ALKS-8700 also known as diroximel fumarate, is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1577222-14-0
Chemical Name: Diroximel fumarate
Synonyms: 2-(2,5-二氧代吡咯烷-1-基)乙基甲基富马酸酯;Diroximel fumarate;2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate;BIIB098;ALKS8700;K0N0Z40J3W;ALKS 8700;4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate;Diroximel Fumarete;Vumerity;diroximel-fumarate;Vumerity (TN);Diroximel fumarate [INN];Diroximel fumarate (USAN/INN);Diroximel fumarate [USAN:INN];GTPL10525;RDC5108;BCP20867
SMILES: O(C(/C(/[H])=C(\[H])/C(=O)OC([H])([H])[H])=O)C([H])([H])C([H])([H])N1C(C([H])([H])C([H])([H])C1=O)=O
Formula: C11H13NO6
M.Wt: 255.2240
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Diroximel fumarate (DRF) is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body[1].
References: [1]. Angela Wehr, et al. Relative Bioavailability of Monomethyl Fumarate after Administration of ALKS 8700 and Dimethyl Fumarate in Healthy Subjects (P1.403). Neurology. Apr 2018.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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