Home > Inhibitors & Agonists > Nuclear Receptor/Transcription Factor > PPAR
Cat. No. Product name CAS No.
DC11751 UHC1

A novel potent, non-agonist PPARγ ligand that blocks CDK5-mediated PPARγ phosphorylation, without the classical agonism.

DC11750 SR-1664 Featured

SR-1664 is a novel potent, non-agonist PPARγ ligand that blocks the Cdk5-mediated phosphorylation in vitro (IC50=80 nM) and in vivo, without the classical agonism.

DC9088 Bezafibrate

Bezafibrate(BM15075) is the first clinically tested dual and pan-PPAR co-agonism.

DC9252 BMS-687453 Featured

BMS687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) α agonist, with an EC50 of 10 nM for human PPARα and ∼410-fold selectivity vs human PPARγ in PPAR-GAL4 transactivation assays.

DC12025 CDDO imidazolide Featured

CDDO-imidazolide is a potent inducer of heme oxygenase-1 and Nrf2/ARE signaling,with potent antiproliferative, differentiating, and anti-inflammatory activities.

DC10727 Elafibranor(GFT505) Featured

Elafibranor is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) with EC50 values of 45 and 175 nM, respectively.

DC9086 Fenofibrate

Fenofibrate is PPARα agonist with EC50 of 18 μM and 30 μM for mouse and human PPARα, respectively.

DC11187 Fonadelpar

Fonadelpar (NPS-005,SJP-0035) is a potent, selective peroxisome proliferator activated receptor δ (PPARδ) agonist for the treatment of corneal disorders..

DC1036 GSK-0660 Featured

GSK-0660 is a selective PPARδ antagonist (IC50 values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ respectively).

DC1035 GSK3787 Featured

GSK3787 is as a potent and selective antagonist of PPARδ with pIC50 of 6.6.

DC2078 GW-7647 Featured

GW 7647 is a potent PPARα agonist with 200-fold selectivity over PPARγ and PPARδ.

DC9904 GW0742 Featured

GW-0742 is a potent and highly selective PPARδ agonist.

DC7149 GW1929 Featured

GW1929 is a synthetic peroxisome proliferator-activated receptor-γ (PPARγ) agonist with IC50 of 6.2 nM and 13 nM for human and mouse, respectively.

DC4233 GW501516 Featured

GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes.

DC2079 GW-9662 Featured

GW9662 is a selective PPAR antagonist, inhibiting PPARγ, PPARα and PPARδ with IC50 of 3.3 nM, 32 nM and 2 μM, respectively.

DC2076 L-165041 Featured

L-165041 is a potent PPARδ agonist (Ki = 6 nM).

DC10772 Lanifibranor Featured

Lanifibranor, also known as IVA-337, is a peroxisome proliferator-activated receptors (PPAR) agonist.

DC12034 MA-0204 Featured

MA-0204 is a potent, selective PPARδ modulator with good pharmacokinetic properties.

DC9897 Palmitoylethanolamide

Palmitoylethanolamide(PEA) is an endogenous fatty acid amide and selectively activates PPAR-α in vitro with an EC50 value of 3.1±0.4 μM.

DC11360 Pemafibrate Featured

Pemafibrate is an orally bioavailable and selective agonist of peroxisome proliferator-activated receptor α (PPARα; EC50 = 1 nM for transcriptional activity), a transcription factor that is essential for regulation of lipid homeostasis.

DCAPI1413 pioglitazone hydrochloride Featured

Pioglitazone Hydrochloride is the hydrochloride salt preparation of Pioglitazone, a specific ligand of PPAR-γ (peroxisome proliferator-activated receptor-γ). Pioglitazone is a thiazolidinedione compound described to produce antiinflammatory and antiarteri

DC11430 RB-394

RB394 is an orally bioavailable and dual modulator of soluble epoxide hydrolase (sEH) and PPARγ.

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