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Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Kynurenine 3-Monooxygenase (KMO)

Kynurenine 3-Monooxygenase (KMO)

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Cat. No. Product Name Field of Application Chemical Structure
DC7656 Ro 61-8048 Featured
Ro 61-8048 is a potent and competitive kynurenine 3-hydroxylase inhibitor (Ki = 4.8 nM, IC50 = 37 nM).
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DC70449 GSK180
GSK180 (GSK-180) is a potent and specific inhibitor of kynurenine-3-monooxygenase (KMO) with IC50 of 6 nM, shows negligible activity against other enzymes on the tryptophan pathway; inhibits the convertion of kynurenine to 3-hydroxykynurenine with IC50 of 2.0 uM in cell-based assays; prevents multiple organ failure in rodent models of acute pancreatitis.
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DC70127 GSK 065
A novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 4.5 nM.
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DC70126 GSK 366
A novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 2.3 nM and 0.7 nM for human KMO and Pf-KMO, respectively.
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