Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC67352 | C12-Diacid-Tri-GalNAc-COOH |
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DC67351 | Tri-GalNAc(OAc)3 Cbz |
Tri-GalNAc(OAc)3 Cbz is a ligand for asialoglycoprotein receptor (ASGPR) where the sugars are protected by acetylation and the tris tertiary amine is protected by benzyloxycarbonyloxy (Cbz). This peracetylated tri-GalNAc(OAc)3 Cbz can be serve as a valuable building block for ASGPR-targeted therapies. Its three branches or arms, each ending in a GalNAc sugar, ensure strong binding to hepatocyte ASGPR. However, the key feature lies in its protective groups: acetylated sugars allow for controlled removal to expose reactive sites for conjugation, while the Cbz-protected amine provides stability and can be selectively cleaved to introduce a reactive amine group for further biomolecule attachment, ultimately enabling researchers to tailor tri-GalNAc(OAc)3 Cbz into customized conjugates for specific therapeutic applications.
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DC72269 | Tri-GalNAc(OAc)3 TFA Featured |
Tri-GalNAc(OAc)3 TFA is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation. tri-GalNAc: triantenerrary N-acetylgalactosamine; LYTAC: lysosome-targeting chimera.
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DC67296 | Galnac GLS-15 Featured |
GLS-15 is a novel GalNAc-derived small molecule structure designed for siRNA delivery.
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DC65561 | GalNac-L96 analog Featured |
GalNAc-L96 analog is an intermediate in the synthesis of the asialoglycoprotein receptor (ASGPR) ligand GalNAc-L96.
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DC66561 | Peracetylated GalNAc succinimidyl pentanoate Featured |
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DC66572 | Peracetylated GalNAc PEG linker-Amino-2 Featured |
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DC66568 | Peracetylated GalNAc PEG linker-Amino-1 Featured |
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DC66564 | Peracetylated GalNAc PEG linker-Acid-1 Featured |
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DC66575 | Peracetylated GalNAc PEG linker-Acid-2 Featured |
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DC66551 | GalNAc-Cluster-HHA-CE Phosphoramidite Featured |
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DC66559 | Peracetylated GalNAc PEG linker-Azide Featured |
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DC66565 | Peracetylated GalNAc-L96-Acid-1 Featured |
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DC65562 | GalNAc-NAG-25 Phosphoramidite Featured |
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DC66549 | GalNAc-NAG-37 Phosphoramidite Featured |
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DC47877 | tri-GalNAc-COOH (acetylation) Featured |
tri-GalNAc-COOH acetylation is the acetylated and modified form of tri-GalNAc-COOH. tri-GalNAc-COOH acetylation can be used for the synthesis of LYTAC.
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DC66574 | Peracetylated GalNAc-L96-1 Featured |
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DC65559 | GalNAc-L96 Phosphoramidite Featured |
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DC66557 | GalNAc-L96 Linker-Azide Featured |
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DC66555 | GalNAc-L96 Linker-Acid Featured |
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DC65560 | GalNAc-L96 free base Featured |
GalNAc-L96 free base, the G-rich oligonucleotides carrying the longer GalNAc linker that can be used for delivery of nucleic acid drugs.
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DC72546 | Tri-GalNAc-NHS ester Featured |
Tri-GalNAc-NHS ester is a LYsosome TArgeting Chimera (LYTAC) and a ligand of asialoglycoprotein receptor (ASGPR). ASGPR is a lysosomal targeting receptor specifically expressed on liver cells, for the degradation of extracellular proteins including membrane proteins. Tri-GalNAc-NHS ester can be used as a protein degrader and it can be used for the research of LYTAC.
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DC66550 | GalNAc-Cluster-COOH Featured |
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DC66548 | GalNAc-Lipid GL3 Featured |
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DC66569 | GalNAc-L96-Amide Featured |
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DC65965 | Tri-GalNAc(OAc)3 Featured |
Tri-GalNAc(OAc)3 is a triantenerrary N-acetylgalactosamine (tri-GalNAc) with an amino group, which is useful precursor for synthesis of GalNAc-LYTAC that engage the asialoglycoprotein receptor for targeted protein degradation. Tri-GalNAc(OAc)3 was first reported in Nat Chem Biol. 2021 Sep;17(9):937-946 (compound ). This product has no formal name at the moment.
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DC46965 | Tri-GalNAc-COOH Featured |
tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research.
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DC65563 | GalNAc-L96-CPG Featured |
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DC65564 | GalNAc-L96-PS Featured |
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DC71975 | TriGalNAc CBz Featured |
TriGalNAc CBz is a GalNAc derivative and tri-GalNAc is an asialoglycoprotein receptor (ASGPR) ligand. TriGalNAc CBz can be used for mRNA drug delivery as well as lysosomal targeted chimerism (LYTAC) studies.
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