Cat. No. | Product name | CAS No. |
DC10906 |
AZ31
Featured
AZ31 is a novel ATM inhibitor. |
2088113-98-6 |
DC10891 |
AZ-32
Featured
AZ32 is an orally bioavailable and blood-brain-barrier penetrating ATM inhibitor (AZ32) that radiosensitizes intracranial gliomas in mice. |
2288709-96-4 |
DC9309 |
AZD-0156
Featured
AZD-0156 is an orally bioavailable ataxia telangiectasia mutated (ATM) kinase inhibitor, with potential chemo-/radio-sensitizing and antineoplastic activities. |
1821428-35-6 |
DC8468 |
AZD-6738
Featured
AZD6738 is an orally active, and selective ATR kinase inhibitor with IC50 of 1 nM. Phase 1/2. |
1352226-88-0 |
DC10526 |
BAY-1895344 HCl(Elimusertib)
Featured
BAY-1895344 is a potent and selective ATM inhibitor. BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride. |
1876467-74-1 |
DC4112 |
CP466722
Featured
CP-466722 is an potent and reversible ATM inhibitor. |
1080622-86-1 |
DC10080 |
GJ103 sodium salt
Featured
GJ103 sodium salt is an active analog of the read-through compound GJ072. |
1459687-96-7 |
DC1067 |
KU-55933
Featured
KU-55933 is a potent and specific ATM inhibitor with IC50 and Ki of 13 nM and 2.2 nM, respectively. |
587871-26-9 |
DC7448 |
KU-60019
Featured
KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM. |
925701-46-8 |
DC3132 |
VE-821
Featured
VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki and IC50 of 13 nM and 26 nM, respectively. |
1232410-49-9 |
DC39113 |
VX-803 (M4344)
VX-803 (M4344) is an ATP-competitive, orally active, and selective inhibitor of ataxia telangiectasia and Rad3 related (ATR) kinase with Ki of < 150 pM. VX-803 (M4344) potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (P-Chk1) phosphorylation with IC50 of 8 nM. VX-803 (M4344) exhibits potential antineoplastic activity. |
1613191-99-3 |