Cat. No. | Product name | CAS No. |
DC11995 |
BI 703704
A novel potent soluble guanylate cyclase (sGC) activator. |
1423067-48-4 |
DC11904 |
Olinciguat (IW-1701)
Featured
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay. |
1628732-62-6 |
DC7782 |
BAY 41-2272
BAY 41-2272 is a soluble guanylate cyclase agonist, activates human mononuclear phagocytes |
256376-24-6 |
DC7787 |
NS-2028
NS 2028 is a specific inhibitor of soluble guanylyl cyclase. |
204326-43-2 |
DC11526 |
Praliciguat
Featured
Praliciguat (IW-1973, IW1973) is a potent, orally available sGC stimulator that concentration-dependently increases the production of cGMP with EC50 of 267 nM. |
1628730-49-3 |
DC7720 |
YC-1(Lificiguat)
Featured
YC-1(Lificiguat) is a soluble guanylyl cyclase(sGC) activator; binds to the heme-containing domain of the β subunit with Kd value of 0.6-1.1 μM in the presence of CO. |
170632-47-0 |
DC40112 |
Plecanatide
Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis. |
467426-54-6 |
DC41629 |
Guanylin(human)
Guanylin(human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism. |
183200-12-6 |
DC41630 |
Guanylin(human) TFA
Guanylin(human) TFA, a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) TFA is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism. |