Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > COMT
Cat. No. Product name CAS No.
DC11485 Tolcapone Featured

Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor.

DC11094 Neluxicapone

DC28087 3-O-Methyltolcapone

3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease.

DC40579 5-Hydroxyferulic acid

5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate.

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