Home > Inhibitors & Agonists > Membrane Transporter/Ion Channel > Sodium Channel
Cat. No. Product name CAS No.
DC9624 Sparteine sulfate pentahydrate Featured

(-)-Sparteine sulfate pentahydrate is a class 1a antiarrhythmic agent and a sodium channel blocker.

DC11984 AMG 8379

A potent and selective voltage-gated sodium channel Nav1.7 antaognist with IC50 of 8.5 nM.

DC11490 A-317567

A-317567 (A317567) is a novel potent acid sensing ion channel (ASIC) blocker with IC50 of 2-30 uM.

DC2061 A-803467 Featured

A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM.

DC11289 AM-0466 Featured

AM-0466 is a potent and selective NaV1.7 Inhibitor (Nav 1.7 IC50 = 21 nM; Nav 1.5 IC50 =>30.0 uM. PXR = 22% @10 uM; CYP 2C9 IC50 = 4.6 uM; CYP3A4 TDI IC50 =>50.0 uM.).

DC9909 AM2099 Featured

AM-2099 is a potent and selective NaV1.7 Inhibitor.

DC11649 Jamaicin (AnCoA4) Featured

AnCoA4 (AnCoA-4, AnCoA 4) is a potent Orai1 channel inhibitor that inhibits store-operated calcium (SOC) with EC50 of 0.88 uM.

DC9193 Carbamazepine Featured

Carbamazepine, a sodium channel blocker, is an anticonvulsant drug.

DC7990 Cariporide

Cariporide is a selective Na+/H+ exchanger isoform 1 (NHE1) inhibitor (IC50 values are 0.05, 3 and 1000 μM for NHE1, NHE3 and NHE2 respectively).

DC8095 Raxatrigine hydrochloride Featured

CNV1014802(GSK-1014802) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor.

DC9623 Flecainide (acetate) Featured

Flecainide(Tambocor) is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.

DC10907 GNE-131 Featured

GNE-131 is a novel NaV1.7 inhibitor with IC50 0.003uM,improving metabolic stability,efficacy in mouse IEM model at C-plasma <2.8uM.

DC8006 GS967(GS-458967) Featured

GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late INa).

DC8213 ICA-121431 Featured

ICA-121431 is a potent, selective inhibitor of the human Nav1.3 and Nav1.1 voltage gated sodium channels (IC50 = 19 nM) with little or no activity against human Nav1.5 or Nav1.7 channels.

DC8124 ETH 2120(Sodium ionophore III) Featured

Ionophore suitable for the assay of sodium activity in blood, plasma, serum. etc. with a solvent polymeric membrane electrode.

DC8797 Lacosamide Featured

Lacosamide (Vimpat; Erlosamide) is a medication developed for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain.

DC8974 Mexiletine Hydrochloride Featured

Mexiletine hydrochloride is a non-selective voltage-gated sodium channel blocker; Class IB anti-arrhythmic compound.

DC8666 Nav1.7-IN-2

Nav1.7-IN-2 is an inhibitor of voltage-gated sodium channels (Nav), in particular Nav 1.7, with IC50 of 80 nM.

DC9796 Nicainoprolhe(Nicainoprol) Featured

Nicainoprolhe is an antiarrhythmic agent,a fast-sodiumchannel blocking drug (class Ib), also protected isolated rat hearts against reperfusion arrhythmias.

DC9001 Oxcarbazepine

Oxcarbazepine inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.

DC10529 PF 05089771 Featured

PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM.

DC10038 PF-01247324 Featured

PF-01247324 is an orally bioavailable, selective and potent NaV1.8 channel blocker that inhibits that exhibits analgesic efficacy in rodent behavioral models of pain.

Page 1 / Total 6 FirstPrevNextLastGoto