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Home > Research Areas > Cancer > Chemotherapeutic Agents

Chemotherapeutic Agents

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Cat. No. Product Name Field of Application Chemical Structure
DC7762 RX-3117 Featured
RX-3117 is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity.
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DC8111 Idarubicin Hydrochloride Featured
Idarubicin Hcl is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor.
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DC4184 Vinorelbine Ditartrate Featured
Vinorelbine (Navelbine) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.
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DCAPI1525 5-Azacytidine Featured
5-Azacytidine is a potent growth inhibitor and a cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. 5-Azacytidine also improves t
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DC2099 cis-Diaminedichloroplatinum Featured
Cisplatin is an inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity.
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DC7530 Voreloxin Featured
Voreloxin(SNS-595; AG 7352) is a small molecule and a naphthyridine analogue with antineoplastic activity; inhibitor of Topo II.
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DC6906 Aprepitant (MK-0869, L-754030) Featured
Substance P antagonists (SPA).
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DC8940 Raltitrexed Featured
Raltitrexed(ZD1694), an inhibitor of thymidylate synthase, is an antimetabolite drug used in cancer chemotherapy.
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DC8149 Pemetrexed disodium Featured
Pemetrexed disodium is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.
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DC5885 Oxaliplatin Featured
Oxaliplatin is a second generation potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of Oxaliplatin was inspired from the eff
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DC9298 thiotepa Featured
N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group.
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DC4182 Temozolomide Featured
Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer.
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DC10406 Imisopasem manganese
Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD.
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DC5882 Fosbretabulin disodium Featured
Fosbretabulin disodium(CA 4DP; CA 4P) is a microtubule destabilizing drug, a type of vascular-targeting agent, a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis.
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DC7069 Daunorubicin HCL Featured
Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.
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DC9013 Cyclophosphamide Featured
Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.
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DC9095 Carboplatin Featured
Carboplatin is a chemotherapy drug by binding to DNA and interfering with the cell's repair mechanism.
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DC7023 Ombrabulin Featured
Ombrabulin (AVE8062) hydrochloride is a synthetic derivative of CA-4-P, which inhibits growth in a large number of drug-resistant animal tumors and carcinogen-induced tumors.
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DC9359 Pralatrexate Featured
Pralatrexate(Folotyn) is an antifolate, and structurally a folate analog.
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DC9050 Melphalan Featured
Melphalan(Sarcolysin; L-PAM) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents; attaches the alkyl group to the guanine base of DNA.
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DC9832 Betulinic acid Featured
Betulinic acid, a pentacyclic triterpene, selectively induces apoptosis in tumor cells, also is a inhibitor of HIV-1 with EC50 of 1.4 μ M.
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DC8962 Tegafur Featured
Tegafur (also known as Ftorafur) is a chemotherapeutic 5-FU prodrug used in the treatment of cancers; is a component of tegafur-uracil.
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DC10444 Sapacitabine (CYC682) Featured
Sapacitabine is an orally bioavailable pyrimidine analogue prodrug with potential antineoplastic activity.
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DC9014 Ifosfamide
Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer.
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DC8946 Gimeracil
Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which degrades pyrimidine including 5-fluorouracil in the blood; inhibits homologous recombination.
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DC2108 Gemcitabine free base
Gemcitabine(Gemzar) belongs to the group of medicines called antimetabolites.
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DC11192 Elacytarabine
Elacytarabine (CP-4055, CP4055) is a fatty acid derivative of cytarabine with potential antineoplastic activity.
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DCAPI1475 Dexrazoxane Hydrochloride
Dexrazoxane Hydrochloride
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DC4186 Cabazitaxel
Cabazitaxel (Jevtana, XRP6258) is a semi-synthetic derivative of a natural taxoid.
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DC8923 AS-1413(Amonafide)
Amonafide(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage.
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