Home > Inhibitors & Agonists > Antibiotics and Antivirals > HCV
Cat. No. Product name CAS No.
DC11823 BMS-929075

A highly potent, selective, orally bioavailable HCV NS5B polymerase inhibitor with IC50 of 9, 4, and 18 nM for GT1a, GT1b, and GT1b-C316N mutant in HCV replicon assay, respectively.

DC11825 MK-8876

A novel, broadly acting non-nucleoside inhibitor of HCV NS5B polymerase with IC50 of 3 nM and 2 nM for GT1b and GT2a, respectively.

DC11731 Ruzasvir

A potent, pan-genotype HCV NS5A inhibitor with replicon EC90 of 0.003, 0.016, 0.067, 0.036, 0.007, and 0.007 nM for GT1a, GT1a L31V, GT1a Y93H, GT2b, GT3a, and Gt4a, respectively..

DC7541 Balapiravir

Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479).

DC5077 Boceprevir(EBP 520; SCH 503034 ) Featured

Boceprevir(EBP 520; SCH 503034 ) is useful for Anti HCV.

DC11081 Coblopasvir

Coblopasvir (KW136, KW-136) is a novel HCV NS5A inhibitor under development for treatment of HCV infection..

DC11214 Cyclophilin inhibitor C31

Cyclophilin inhibitor C31 (SMCypI C31) is a small-molecule cyclophilin (CypA) inhibitor (SMCypI) with PPIase inhibition IC50 of 0.1 uM, displays anti-HCV activity (HCV Gt1b replicon EC50=0.4 uM) and disrupts the CypA-NS5A interaction.

DC7394 Daclatasvir dihydrochloride (BMS-790052) Featured

Daclatasvir (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture.

DC8238 Danoprevir Featured

Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A.

DC10818 ABT-493(Glecaprevir) Featured

Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM.

DC11494 INX-08189

INX-08189 is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay.

DC8178 Beclabuvir(BMS-791325)

non-nucleoside inhibitor of the NS5B

DC8183 Paritaprevir(Veruprevir ABT-450) Featured

NS3/4A protease inhibitor

DC10728 Pibrentasvir(ABT-530) Featured

Pibrentasvir is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6.

DC4121 PSI6130 Featured

PSI-6130(R 1656) is a Hepatitis C Virus Nucleoside Inhibitor. PSI-6130(R 1656) is useful for Antiviral agents.

DC9462 R-7128(Mericitabine) Featured

R-7128(Mericitabine) is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, with activity across all HCV genotypes.

DC8190 Ravidasvir hydrochloride (PPI-668) Featured

Ravidasvir(PPI-668) is a NS5A Inhibitor.

DC8612 Simeprevir(TMC-435)

Simeprevir (TMC 435350) is a potent inhibitor of HCV NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM).

DC9463 Tegobuvir (GS-9190; GS 333126) Featured

Tegobuvir (GS-9190; GS 333126) is a non-nucleoside nonstructural protein (NS)5B polymerase inhibitor.

DC1008 Telaprevir (VX-950) Featured

Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM.

DC10104 VX222(Lomibuvir) Featured

VCH-222(Lomibuvir) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L.

DC9751 Velpatasvir(GS5816) Featured

Velpatasvir(GS-5816) is a potent and selective Hepatitis C virus NS5A inhibitor.

Page 1 / Total 4 FirstPrevNextLastGoto