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Cat. No. Product name CAS No.
DC11768 TAM-16

A benzofuran class inhibitor of M. tuberculosis Pks13 (Polyketide Synthase 13).

DC11531 Teslexivir

A first-in-class, small molecule protein-protein inhibitor of the interaction between the E1 and E2 proteins of HPV types 6 and 11.

DC12012 PD 404182 Featured

PD 404182 is a high affinity inhibitor of KDO 8-P synthase (Ki = 26 nM). Also inhibits dimethylarginine dimethylaminohydrolase 1 (DDAH1). Exhibits antiangiogenic and antiviral activity in vitro. Putative antibiotic against gram-negative bacteria.

DC11823 BMS-929075

A highly potent, selective, orally bioavailable HCV NS5B polymerase inhibitor with IC50 of 9, 4, and 18 nM for GT1a, GT1b, and GT1b-C316N mutant in HCV replicon assay, respectively.

DC11892 Elsulfavirine Featured

A new-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV-1 infections, the prodrug of the active compound VM-1500A..

DC11998 IND-114338

A novel antiprion compound with EC50 of 68 nM, significantly increases monoglycosylated/diglycosylated PrPSc..

DC11534 Sudoterb Featured

A novel anti-TB agent that has an MIC range of 0.06-0.5 ug/mL..

DC11535 Sudoterb dihydrchloride

A novel anti-TB agent that has an MIC range of 0.06-0.5 ug/mL..

DC11997 IND125

A novel brain penetrant antiprion compound with EC50 of 57 nM, prevents both PrP(Sc) accumulation and astrocytic gliosis in the cerebrum.

DC11628 HIV-1 Integrase Inhibitor 1

A novel compound that disrupts the HIV-1 integrase LEDGF interaction.

DC11811 SCY-078

A novel orally bioavailable fungal beta-1,3-D glucan synthetase inhibitor against Candida species C. glabrata (MIC 0.03 to 0.25 ug/ml), C. parapsilosis (MIC 0.06 to 0.25 ug/ml).

DC11854 IDX899

A novel potent, selective HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with EC50 of 1, 1.3, 2.8 and 11 nM for WT, K103N, Y181C and K103N/Y181C, respectively.

DC11527 Quilseconazole Featured

A novel selective, orally available fungal CYP51 (lanosterol 14-α-demethylase) inhibitor.

DC11877 F3406

A novel small-molecule arenaviruse inhibitor that exhibits strong anti-LCMV activity (IC50<1 uM) without cell toxicity.

DC11825 MK-8876

A novel, broadly acting non-nucleoside inhibitor of HCV NS5B polymerase with IC50 of 3 nM and 2 nM for GT1b and GT2a, respectively.

DC22771 Proxalutamide Featured

Proxalutamide (GT-0918) is a nonsteroidal antiandrogen (NSAA) – specifically, a selective high-affinity silent antagonist of the androgen receptor (AR) for the potential treatment of COVID-19, prostate cancer, and breast cancer.

DC23957 RO-9187 Featured

A potent HCV NS5B RNA polymerase inhibitor.

DC11807 HIV InSTI-1

A potent HIV integrase strand transfer inhibitor (InSTIs) with IC50 of 8 nM in HIV replication assay.

DC11806 MK-0536

A potent HIV-1 integrase strand transfer inhibitor with IC50 of 33 nM, 9.5 nM, 40 nM, 20 nM and 237 nM for wt IN, IN Y143R, IN N155H, G118R and IN G140S-Q148H, respectively.

DC11771 AZ-27

A potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively.

DC11773 BI Compound D

A potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 89 nM.

DC11772 AZD-4316

A potent respiratory syncytial virus (RSV) fusion inhibitor..

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