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Home > Research Areas > Inflammation/Autoimmune Disease > Psoriasis

Psoriasis

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Cat. No. Product Name Field of Application Chemical Structure
DC10193 Seletalisib Featured
Seletalisib (UCB5857) is potent and selective PI3Kδ inhibitor with an IC50 of 12 nM.
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DCAPI1551 Tacalcitol Featured
Tacalcitol is a synthetic vitamin D3 analog. This compound has been shown to regulate calcium levels and induce nerve growth factor production in epidermal keratinocytes. Additionally, Tacalcitol has been noted to promotes normal bone development by regul
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DC7063 Apremilast Featured
Apremilast(CC10004) is a novel small molecule inhibitor of PDE4 with an IC50 value of 74 nM.
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DC11890 Delgocitinib Featured
Delgocitinib (JTE-052, LEO 124249) is a potent, selective, orally active, pan-JAK inhibitor with IC50 of 2.8, 2.6, 13 and 58 nM for JAK1,2,3 and Tyk2, respectively.
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DC11530 Tapinarof (Benvitimod; GSK2894512) Featured
Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC50 of 13 nM. Tapinarof resolves skin inflammation in mice.
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DC8169 Solcitinib(GLPG0778) Featured
Solcitinib, also known as GSK2586184 or GLPG0778, is a Janus kinase 1 (JAK1) inhibitor.
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DC12488 PF-06700841 tosylate Featured
PF-06700841 is an inhibitor of JAK1 and TYK2 kinases. PF-06700841 has been investigated for the treatment of psoriasis and lupus.
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DC10787 GSK2982772 Featured
GSK2982772 is a potent and ATP competitive RIP1 inhibitor with an IC50 of 16 nM.
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DC9713 GSK2981278 Featured
GSK2981278 is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma).
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DC10893 Parimifasor Featured
Parimifasor is an immunomodulator, with anti-inflammatory activity.
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DC9956 BFH772 Featured
BFH772 is a potent oral VEGFR2 inhibitor, which is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM.
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DC11844 VTP-43742
VTP-43742 (VTP43742) is a highly potent, selective, oral RORγt inverse agonist for the treatment of autoimmune disorders, including multiple sclerosis and psoriasis..
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DC11734 PF-06263276
PF-06263276 (PF06263276, PF 6263276) is a potent, selective pan JAK inhibitor with IC50 of 2.2, 23.1, 59.9 and 29.7 nM for JAK1, JAK2, JAK3, and TYK2, respectively.
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DC8997 Cromolyn sodium
Cromolyn sodium is an antiallergic drug.
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DCAPI1409 Maxacalcitol
22-Oxacalcitriol is a Vitamin D3 analog which is Non-calcemic as well as a VDR ligand. 22-Oxacalcitriol has been shown to decrease parathyroid hormone (PTH) mRNA expression in vitro. Additionally has been noted to exhibit similar effects to calcitriol in
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