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Home > Research Areas > Metabolic Disorder > Osteoporosis

Osteoporosis

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Cat. No. Product Name Field of Application Chemical Structure
DC60813 NPS-2143(SB 262470A )
NPS-2143(SB 262470A ) is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively.
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DCAPI1559 Calcifediol Featured
Calcifediol is a major circulating metabolite of vitamin D3, acting as a competitive inhibitor with an apparent Ki of 3.9 μM, suppresses PTH secretion and mRNA (ED50=2 nM).
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DC6401 Odanacatib (MK 0822) Featured
Odanacatib (MK 0822) is a potent, selective, and neutral inhibitor of human and rabbit cathepsin K with IC50 of 0.2 nM and 1 nM , respectively.
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DCAPI1445 strontium ranelate
Strontium Ranelate is a bone metabolism modulator that inhibits bone resorption while maintaining bone formation. Commonly used as an antiosteoporotic.
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DC4136 NPS-2143 HCL
NPS 2143 hydrochloride is a selective CaSR (Ca2+-sensing receptor) inhibitor and antagonist, shown to block increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells with an IC50 of 43 nM. NPS 2143 hydrochlori
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DCAPI1034 Alendronate (Fosamax)
Alendronate (Fosamax)
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