A novel potent ULK1 inhibitor with IC50 of 11 nM..

LYN-1604 is a potential ULK1 agonist with IC50 of 1.66 μM against MDA-MB-231 cells and it binds to wild-type ULK1 with a binding affinity in the nanomole range (Kd=291.4 nM).

MRT67307 is a potent and dual IKKϵ and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively.

SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor.

SR-20295 (SR20295) is a novel potent ULK1 inhibitor with IC50 of 45 nM..