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Cat. No. Product name CAS No.
DC11603 SR-19871

A novel potent ULK1 inhibitor with IC50 of 11 nM..

DC10715 LYN-1604 Featured

LYN-1604 is a potential ULK1 agonist with IC50 of 1.66 μM against MDA-MB-231 cells and it binds to wild-type ULK1 with a binding affinity in the nanomole range (Kd=291.4 nM).

2088939-99-3
DC10635 MRT67307 HCl Featured

MRT67307 is a potent and dual IKKϵ and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively.

1190378-57-4
DC8316 SBI-0206965 Featured

SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor.

1884220-36-3
DC11604 SR-20295

SR-20295 (SR20295) is a novel potent ULK1 inhibitor with IC50 of 45 nM..

2166091-48-9
DC9702 MRT68921 Featured

MRT68921 is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.

1190379-70-4
DC70343 DCC-3116

DCC-3116 (DCC3116) is a first-in-class, selective inhibitor of ULK1/2 kinases (IC50=4.7/35 nM) and autophagy.

DC73150 MR-2088

MR-2088 is a potent and selective ULK1/2 inhibitor with IC50 of 2.0 nM and MST Kd value of 1.5-4.4 nM (ULK1), efficiently inhibits autophagy.

2922531-69-7
DC74587 XST-14

XST-14 is a potent, competitive, and highly selective inhibitor of ULK1 and exhibits an IC50 of 26.6 nM in an in vitro ULK1 kinase activity assay, respectively. XST-14 reduces the phosphorylation of the ULK1 downstream substrate and induces autophagy inhibition. It exhibits antitumor effects.

2607143-50-8
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