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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC9830 | AM-2394 Featured |
AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phosphorylation of glucose to glucose-6-phosphate.
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| DC73740 | TMG-123 |
TMG-123 (TMG123) is a potent small molecule activator of glucokinase (GK) with EC50 of 0.35 and 0.32 uM for human liver and pancreas GK, respectively.
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| DC73739 | GKM-001 |
GKM-001 is a potent, liver-selective small molecule activator of glucokinase (GKA), demonstrates glucose lowering effect without hypoglycemia in normal and type II diabetes mellitus (T2DM).
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| DC73738 | GKA23 |
GKA23 is a potent, small molecule glucokinase (GK) activator with EC50 of 152 nM for glucokinase activation in 5 mM glucose, increases glucose uptake in primary rat hepatocytes with EC50 of 201 nM.
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| DC72666 | BMS-820132 Featured |
BMS-820132 (BMS 820132) is potent, selective, partial glucokinase (GK) activator with AC50 of 29 nM.
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| DC8041 | MK-0941 Featured |
MK-0941 is a novel Glucokinase activator (GKA)
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| DC71545 | Cadisegliatin |
Cadisegliatin (TTP-399) is a potential liver-selective glucokinase (GK) activator for type 2 diabetes and has antihyperglycaemic activity.
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| DC9690 | Sinogliatin (HMS5552, RO5305552) Featured |
Sinogliatin (HMS5552, RO5305552) is a mall molecule glucokinase (GCK; GK) activator.
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| DC49736 | Glucokinase activator 3 |
Glucokinase activator 3 is a potent and full Glucokinase (GK) activator with an AC50 of 38 nM. Glucokinase activator 3 has the potential for the research of type 2 diabetes.
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| DC10101 | AMG-3969 Featured |
AMG-3969 is a potent glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor with an IC 50 of 4 nM.
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| DC47198 | IHVR-11029 |
IHVR-11029 is a small molecule inhibitor of ER α-glucosidases, with an EC50 of 0.09 μM.
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| DC28983 | GKA50 |
GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose). GKA50 stimulates insulin release from mouse islets of Langerhans and MIN6 cells. GKA50 shows significant glucose lowering in high fat fed female rats.
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| DC28744 | AR453588 hydrochloride |
AR453588 hydrochloride is a potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM. AR453588 hydrochloride shows anti-hyperglycemic activity.
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| DC28743 | AR453588 |
AR453588 is a potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM. AR453588 shows anti-hyperglycemic activity.
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| DC9454 | Ro 28-1675 |
Ro 28-1675 (Ro 0281675) is a potent allosteric GK activator with a SC1.5 value of 0.24± 0.0019 uM.
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