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Home > Research Areas > Cardiovascular Disease > Atherosclerosis

Atherosclerosis

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Cat. No. Product Name Field of Application Chemical Structure
DC9861 BMS-779788(XL-652) Featured
BMS-779788(XL652) is a novel small-molecule modulator of the Liver X Receptor (LXR), a nuclear hormone receptor implicated in a variety of cardiovascular and metabolic disorders.
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DC7397 Darapladib Featured
Darapladib is a selective and orally active inhibitor of Lp-PLA2 (IC50= 270 pM)
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DC7804 Anacetrapib(MK0859) Featured
Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3.
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DC9609 Terutroban Featured
Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist.
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DC7519 Torcetrapib Featured
Torcetrapib is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3.
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DC2072 LXR623 Featured
LXR-623 is a novel Liver X Receptor modulator
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DC9456 MK-0354
MK-0354 is a partial agonist of GPR109a receptor, for hGPR109a/ mGPR109a with EC50 of 1.65/1.08 μM, showed no activation of GPR109b.
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