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Home > Research Areas > Other Indications > Steatohepatitis

Steatohepatitis

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Cat. No. Product Name Field of Application Chemical Structure
DC9995 MGL-3196(Resmetirom) Featured
MGL-3196 is a potent and highly selective thyroid hormone receptor β agonist in clinical trials for the treatment of dyslipidemia.
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DC10737 Tropifexor (LJN452) Featured
Tropifexor (LJN452) is a highly potent non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).
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DC9873 Selonsertib(GS-4997) Featured
Selonsertib(GS-4997)is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.
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DC8390 Oltipraz Featured
Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Phase 3.
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DC10173 Firsocostat(ND-630,GS-0976) Featured
ND-630 is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively.
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DC9762 Emricasan Featured
Emricasan (IDN-6556, PF-03491390) is a potent irreversible pan-caspase inhibitor.
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DC10868 Cilofexor Featured
Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.
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