Home > Inhibitors & Agonists > Membrane Transporter/Ion Channel > CRAC Channel
Cat. No. Product name CAS No.
DC9962 YM-58483 Featured

YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals.

DC40200 RO2959 monohydrochloride

RO2959 monohydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 monohydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1/Stim1 channels with an IC50 of 25 nM. RO2959 monohydrochloride is also a potent inhibitor of human IL-2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways.

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