Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Beta-secretase (BACE)
Cat. No. Product name CAS No.
DC11889 Atabecestat

Atabecestat (JNJ-54861911, JNJ54861911) is a novel potent, oral beta-secretase (BACE) inhibitor for treatment of Alzheimer's Disease.

DC9946 Lanabecestat(AZD3293,LY-3314814)

AZD3293 is a potent and selective orally active, brain-permeable BACE1 inhibitor,currently in development as a potential treatment for early Alzheimer’s disease.

DC8400 AZD3839 Featured

AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.

DC11105 Umibecestat

beta-secretase inhibitor.

DC11551 Elenbecestat

Elenbecestat (E2609) is a novel potent, oral BACE1 inhibitor for treatment of Alzheimer's disease..

DC5180 LY2811376 Featured

LY2811376 is the first orally available non-peptidicβ-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM.

DC5053 LY2886721 Featured

LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.

DC9901 Verubecestat (MK-8931) Featured

MK-8931 is a BACE1 inhibitor. MK-8931 binds significantly to β-secretase.

DC40115 Kushenol C

Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC50 of 5.45 μM.

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