Cat. No. | Product name | CAS No. |
DC9137 |
Timolol Maleate
Featured
(S)-Timolol maleate, is a potent non-selective β-adrenergic receptor antagonist (Ki values are 1.97 and 2.0 nM for β1 and β2 receptor subtypes respectively). |
26921-17-5 |
DCAPI1496 |
Ambrisentan
Featured
A nonpeptide endothelin ETA receptor antagonist. Antihypertensive. |
177036-94-1 |
DC11547 |
LY-2562175
Featured
A novel potent, selective, partial FXR agonist with EC50 of 193 nM. |
1103500-20-4 |
DC11893 |
Firibastat
A potent, orally active, centrally acting aminopeptidase inhibitor, the prodrug of the specific and selective aminopeptidase A inhibitor EC33. |
648927-86-0 |
DC11850 |
MK-7145
A potent, selective, and oral renal outer medullary potassium channel (ROMK) inhibitor with IC50 of 68 nM. |
1255204-84-2 |
DCAPI1468 |
Rosuvastatin Calcium
Featured
A selective, competitive inhibitor of HMG-CoA reductase, that is also antilipemic. |
147098-20-2 |
DCAPI1495 |
Aliskiren Hemifumarate
Featured
Aliskiren hemifumarate(CGP 60536) is a direct renin inhibitor with IC50 of 1.5 nM. |
173334-58-2 |
DC7804 |
Anacetrapib(MK0859)
Featured
Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3. |
875446-37-0 |
DC5114 |
Apixaban (BMS 562247-01)
Featured
Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively. |
503612-47-3 |
DC9020 |
Atenolol
Atenolol is a selective β1 receptor antagonist. |
29122-68-7 |
DCAPI1442 |
Atorvastatin Calcium
Featured
Atorvastatin Calcium |
134523-03-8 |
DC1094 |
Avasimibe (CI-1011)
Featured
Avasimibe inhibits ACAT and CYP2C9 with IC50 of 3.3 μM and 2.9 μM, respectively. |
166518-60-1 |
DC8004 |
AZD6482
Featured
AZD6482 is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ. |
1173900-33-8 |
DC4210 |
Azilsartan kamedoxomil
Featured
Azilsartan medoxomil is an angiotensin II receptor antagonist indicated for the treatment of mild to moderate essential hypertension. |
863031-24-7 |
DCAPI1469 |
azilsartan
Featured
Azilsartan(TAK-536) is a specific and potent angiotensin II type 1 receptor antagonist with IC50 of 2.6 nM. |
147403-03-0 |
DC9596 |
Azimilide (Dihydrochloride)
Azimilide 2Hcl(NE-10064 2Hcl) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes. |
149888-94-8 |
DC7782 |
BAY 41-2272
Activator of soluble guanylyl cyclase (sGC); acts at a nitric oxide (NO)-independent regulatory site in the sGC α1 subunit. Inhibits platelet aggregation (IC50 = 36 nM) and phenylephrine-induced contractions of rabbit aorta (IC50 = 0.30 μM). Also reduces vascular smooth muscle growth through cAMP- and cGMP-dependent PKA and PKG pathways.. For the detailed information of BAY 41-2272, the solubility of BAY 41-2272 in water, the solubility of BAY 41-2272 in DMSO, the solubility of BAY 41-2272 in PBS buffer, the animal experiment (test) of BAY 41-2272, the cell expriment (test) of BAY 41-2272, the in vivo, in vitro and clinical trial test of BAY 41-2272, the EC50, IC50,and affinity,of BAY 41-2272, Please contact DC Chemicals. |
256376-24-6 |
DC7373 |
Betrixaban
Featured
Betrixaban (PRT-054021) is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM(inhibition of Factor 10a). |
330942-05-7 |
DCAPI1112 |
BIBR 953(Dabigatran)
Featured
BIBR 953 (Dabigatran, Pradaxa) is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate. |
211914-51-1 |
DC1010 |
BIBR-1048 (Dabigatran etexilate)
Featured
BIBR-1048 (Dabigatran) is an anticoagulant from the class of the direct thrombin inhibitors. |
211915-06-9 |
DC9252 |
BMS-687453
Featured
BMS687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) α agonist, with an EC50 of 10 nM for human PPARα and ∼410-fold selectivity vs human PPARγ in PPAR-GAL4 transactivation assays. |
1000998-59-3 |
DC9861 |
BMS-779788(XL-652)
BMS-779788(XL652) is a novel small-molecule modulator of the Liver X Receptor (LXR), a nuclear hormone receptor implicated in a variety of cardiovascular and metabolic disorders. |
918348-67-1 |